S2M3 Histology Kallie Female Reproduction

Front 1

T/F
The granulosa layer of a secondary follicle responds to LH.

Back 1

False, the theca interna responds to LH.

The granulosa layer of secondary follicle produces LH receptors but not not itself respond to LH.

Front 2

T/F
The theca externa is highly vascularized.

Back 2

False, the theca INTERNA is highly vascularized.

Front 3

T/F
The theca interna is separated from the theca externa by a basal lamina

Back 3

False, the theca interna is separated from the granulosa layer by a basal lamina.

Front 4

T/F
The secondary follicle contains a secondary oocyte.

Back 4

False, secondary follicle contains a primary oocyte

Front 5

T/F
The granulosa layer converts androstenedione to estrogens.

Back 5

TRUE!!!!

Front 6

T/F
FSH stimulates the primordial follicles to develop.

Back 6

False, it it not dependent upon FSH

Front 7

T/F
FSH stimulates the production of progesterone in the corpus luteum.

Back 7

False

Front 8

T/F
The corpus luteum responds to estrogen stimulation.

Back 8

False, corpus luteum responds to LH or hCG

Front 9

T/F
Inhibin blocks FSH secretion

Back 9

True!

Front 10

T/F
LH stimulates proliferation of the granulosa cells in the primary follicle.

Back 10

False, activin stimulates proliferation of the granulosa cells in the primary follicle.

Front 11

T/F
Medullary region of ovary is rich in blood vessels and CT.

Back 11

True

Front 12

What tissue gives rise to follicular cells?

Back 12

Germinal epithelium in the cortical region of the ovary

Front 13

What secretes OMI (oocyte maturation inhibitor)?

Back 13

Follicular cells

Front 14

Primordial follicle has a balbiani body and a annulate lamellae. What are these things?

Back 14

Balbiani body sits near the nucleus and is composed of golgi membranes, E.R., mitochondria and lysosomes.

Annulate lamellae are found in ooplasm and resemble profiles of nuclear envelope

Front 15

A primary follicle has follicular cells, theca folliculi, and filopodia. What is the difference between a unilaminar and multilaminar primary follicle?

Back 15

Unilaminar primary follicle has a single follicular cell layer.

Multilaminar primary follicle has a stratified layer of follicular cells.

Front 16

Where are cortical granules and what do they do?

Back 16

They are found just beneath the plasma membrane of the oocyte and contain proteolytic enzymes that are released during fertilization to prevent polyspermy.

Front 17

What two layers do the theca folliculi differentiate into?

Back 17

1.) Theca interna
2.)Theca externa

Front 18

Which thecal layer has LH receptors and can produce androstenedione?

Back 18

Theca interna

Front 19

Which thecal layer is highly vascularized with cuboidal epithelium?

Back 19

Theca interna

Front 20

Which thecal layer is mainly smooth muscle cells and collagen fibers?

Back 20

Theca externa

Front 21

Which follucular phases depends on FSH?

Back 21

Only secondary and Mature Graafian follicles.

Front 22

A secondary follicle is recognized by fluid filled spaces called __________.
What substances are in this fluid?

Back 22

Antrum.

The fluid (liquor folliculi) is an exudate of plasma with GAGs, proteoglycans and hormones

Front 23

Which hormones is responsible for increasing the number of granulosa cells and the number of intercellular spaces?

Back 23

FSH

Granulosa cells have FSH receptors
(they also have LH receptors after ovulation to make progesterone)

Front 24

When there is a single antrum space, what type of follicle is this?

Back 24

Mature Graafian Follicle (preovulatory follicle)

Front 25

What is a cumulus oophorus and which follicle is it associated with?

Back 25

part of the granulosa which surrounds the oocyte but is also continuous with the granulosa surrouding the follicle (forms an oocyte bridge).

Found in a mature graafian follicle

Front 26

What thecal layer does LH stimulate?

What are they products?

Back 26

LH stimulates theca interna cells to make androstenedione.

Front 27

What stimulates granulosa cells to use androgens to make estrogen?

Back 27

FSH stimulates granulosa cells to make aromatase; which catalyzes androgens to estrogens.

Front 28

What causes the LH surge?

Back 28

immediately before ovulation, estrogen begins to become a positive feedback molecule causing the release of EVEN MORE LH, results in an LH surge.

Front 29

List the sequence of events occuring after LH surge. (5 things).

Back 29

1.) oocyte continues through meiosis 1
2.) formation of secondary oocyte and polar body
3.) secondary oocyte is arrested in metaphase of M2
4.) ovulation of secondary oocyte on dya 14
5.) Formation of the corpus leuteum.

Front 30

*Don't know if this is correct but....

other than the LH surge, the increase of estrogen b4 ovulation also causes ....

Back 30

negative feedback on FSH release from pituitary.

Front 31

Region of the ovary that is blanched and avascular before ovulation is known as the_______.

Back 31

Stigma

This is the area where the oocyte ruptures into the abdomen.

Front 32

After ovulation, the remnant of the graafian follicle forms a blood clot and is called the __________.
How is this clot removed?

Back 32

Corpus hemorrhagicum.

Phagocytes will remove the clot.

Front 33

High LH levels will turn a corpus hemorrhagicum into a corpus luteum. The organ is highly vascularized and composed of what two cell types?

Back 33

Granulosa-lutein cells and Theca-lutein cells

Front 34

After ovulation, corpus leutum granulosa lutein cells will begin synthesizing TONS of what hormone?

Back 34

Progesterone.

Front 35

Progesterone and estrogen secreted by the corpus luteum will have a negative feedback on what?

Back 35

Progesterone inhibits LH
Estrogen inhibits FSH
(Low FSH will prevent a second ovulation!!!)