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20 Cards in this Set
- Front
- Back
ASTHMA OVERVIEW
- Short term goal in the treatment of asthma? - Long term goal in the treatment of asthma? |
- Symptomatic treatment
- Treat the Underlying Inflammatory process |
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ASTHMA OVERVIEW
- what drug categories are used in the treatment of asthma? |
- Muscarinic blockers
- Beta2 agonists - Corticosteroids - Theophylline - Cromolyn sodium - Leukotriene antagonists |
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CORTICOSTEROIDS
- list the names of INHALED corticosteroids asthma - list the names of PO or IV corticosteroids for asthma |
- BecloMethasone
- Budesonide - Fluticasone - Mometasone - Prednisone - Prednisolone |
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INHALED CORTICOSTEROIDS
- inhaled corticosteroids are indicated for what type of patients? |
- those who require regular bronchodilators
- asthma not well controlled |
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INHALED CORTICOSTEROIDS
- what are some side effects that may be seen with using inhaled corticosteroids? |
- Candidiasis (Oropharyngeal)
- ?Retardation of growth in kids? |
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INHALED CORTICOSTEROIDS
- Inhaled corticosteroids is the cornerstone of ______ asthma treatment in people with _______ to _____ asthma. |
- Chronic
- Moderate to Severe |
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INHALED CORTICOSTEROIDS
- Inhaled corticosteroids MOA in order to INHIBIT? - Inhaled corticosteroids MOA in order to PREVENT? |
- WBC
- Infiltration (cellular infiltration) - Inflammatory mediators (TNFa & ILs) |
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PO / IV CORTICOSTEROIDS
- PO or IV corticosteroids are generally reserved for ______ & ______ asthma. |
- Severe & Acute
- Persistent |
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PO / IV CORTICOSTEROIDS
- SE with PO / IV corticosteroids |
- Cushings
- Osteoporosis - Redistribution of fat - sTriae - Interruption of Glucose metabolism - Crappy wound healing |
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BETA 2 AGONIST
- indications for use in what asthma type - prophylactic indications in what asthma type |
- Acute Bronchoconstriction
- Prophylaxis of exercise-induced asthma |
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BETA 2 AGONIST
- asthma treatment with Beta2 agonist dose NOT do what? |
- resolve underlying inflammation
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BETA 2 AGONIST
- effectiveness of Beta 2 agonist will wane if? - what is the exception to this rule? |
- with Chronic use
- Salmeterol |
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BETA 2 AGONIST
- list the Beta2 agonists |
(MAST IF Asthma)
- Metoprotenolol - Albuterol - Salmeterol - Terbutaline - Isoproterenol - Formoterol |
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BETA 2 AGONIST
- which Beta2 agonists are used for acute asthma treatments (aka - short acting Beta2 agonists) - administered how during asthma attacks? |
- Metoprotenolol
- Albuterol - Nebulizer - IV |
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BETA 2 AGONIST
- which Beta2 agonists are used for chronic asthma management? - administered how? - usually administered with what other therapy |
- Salmeterol
- Formoterol - Inhalation BID - Corticosteroids |
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BETA 2 AGONIST
- Long acting Beta2 agonist drugs are NOT appropriate for what? |
- Acute exacerbations of asthma
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BETA 2 AGONIST
- describe the morphology of the Beta 2 receptor - list the actions of Beta2 stimulation |
- Gs receptor
(VBUG) - Vasodilation - Bronchodilation - Uterine SM relaxation - Glycogenolysis |
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BETA 2 AGONIST
- Terbutaline can also be clinically used for what non-asthma purpose? |
- reduce premature uterine contractions
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BETA 2 AGONIST
- Salmeterol works for how long? - Salmeterol may induce what SE? |
- more than 12 hours
- Arrhythmia - Tremors |
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BETA 2 AGONIST
- which Beta2 agonist should be used as a prophylaxis? |
- Salmeterol
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