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12 Cards in this Set
- Front
- Back
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What are 4 main effects of the Rubella virus?
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1. Vasculopathy
2. Inhibition of Mitosis 3. Chromosomal breakage. 3. Infarcts -VICI- |
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What is the classic triad of congenital rubella?
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1. Heart deformity
2. Cataracts 3. Deafness |
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Is there a treatment for rubella?
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No
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What population is targeted with the rubella vaccine?
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Child-bearing age/college students
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How is rubella not diagnosed?
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Cell culture - it produces no CPE.
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How IS rubella diagnosed?
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Via the production of interferon in a culture media after secondary exposure to the virus.
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What type of virus is the rubella virus?
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Enveloped ssRNA virus
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What happens after a primary infection with rubella?
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Protection for LIFE!
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What symptoms are seen in a rubella RE-infection?
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-Scanty virus excretion from throat for 1-4 days.
-Rise in IgG titer |
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What symptoms are seen in PRIMARY rubell infectiona?
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Rash, Virus excr 1-3 days, viremia, transplacent. passage, IgG AND IgM antibodies.
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Are the symptoms from a rubella vaccine more like primary or secondary infections?
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PRimary
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How are vaccine symptoms NOT like primary infection?
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-Shorter incubation (7-10 days inst. of 14-21)
-Rarely a rash |
