Rosenberg Drugs Of Abuse

Front 1

describe cross tolerance

Back 1

use of one drug that will induce tolerance, usually functional, to another drug, so it has no effects. such as high doses of methadone for use in heroin addict

Front 2

describe cross dependence

Back 2

the ability of one drug to maintain the dependence produced by another (thus a second drug can be taken to maintain the homeostasis that was usually dependent on the first drug)

Front 3

LSD MOA:

Back 3

both agonist and antagonist at various 5HT-Rs.

Front 4

what drug can help in treating someone high on LSD

Back 4

benzodiazepines

Front 5

LSD - physical dependence?

Back 5

no physical dependence

Front 6

PCP MOA:

Back 6

blocks NMDA-Glutamate-R

Front 7

how can you differentiate the effects of LSD and PCP

Back 7

-both have hallucinations, HTN, tachycardia
LSD: color perception is intensified; paranoia/depressed mood (bad trip)
PCP: may become violent and aggressive

Front 8

marijuana MOA:

Back 8

works on GprotRs that are inhibitory, "specific cannabinoid receptors"

Front 9

therapeutic uses of marijuana?

Back 9

reduce intraocular pressure
reduce N/V