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5 Cards in this Set
- Front
- Back
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on what and where do the methylxanthines act?
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caffeine, theophylline act in the CNS and on SMC to inhibit adenosine-Rs (leads to more NE release) and inhibit PDEs (leads to more cAMP)
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amphetamine acute toxicity is usually due to:
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CV effects
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discuss amphetamines/cocaine and dependence
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no physical dependence
high psychological dependence |
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what is ampetamine MOA
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indirect adrenergic agonist - enters presyn neuron via uptake 1 (thus inhibitd by cocaine) and stimulates the release of NE
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discus amphetamines and tolerance
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pronounced tolerance develops to amphetamines. (remember tolerance = tachyphylaxis)
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