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20 Cards in this Set

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  • Back
As a treatment for osteopetrosis (marble bone disease), bone marrow transplant is done to provide which of the following cells:

a. Chondrocytes
b. Osteoclasts
c. Osteoblasts
d. Osteocytes
b. Osteoclasts
Which of the following is not true about acute bacterial osteomyelitis:

a. Metaphyseal plate is most common site of infection in children
b. Is commonly hematogenous in origin
c. Usually has poor prognosis
d. Staphylococcus is often the etiologic agent
c. Usually has poor prognosis
All but one of the following are true about degenerative osteoarthritis:

a. There is degeneration of articular cartilage
b. In increasing frequency of disease with advancing age
c. Involvement commonly is with large joints - hips and knees
d. Is of an autoimmune etiology
d. Is of an autoimmune etiology
Characteristics of rheumatoid arthritis include all but which one of the following:

a. Has an autoimmune etiology
b. Results from wear and tear on large joints (knees and hips)
c. Pannus forms wiping out the cartilage
d. Involves the small joints of hands and feet
b. Results from wear and tear on large joints (knees and hips)
Osteoporosis, or increased resorption of bone, and a resulting decrease in bone mass, is the result of:

a. Increased osteoclastic activity
b. Degeneration of articular cartilage
c. A hereditary disorder
d. Wear and tear on the large weight-bearing joints
a. Increased osteoclastic activity
The principal growth plate disorder in osteopetrosis is:

a. Failure of mineralization of bone
b. Failure of removal of calcified cartilage
c. Excessive production of osteoid
d. Excessive production of cartilage
b. Failure of removal of calcified cartilage
Rheumatoid arthritis is commonly characterized by:

a. Involvement of the large joints (hips, knees)
b. Finding a layer of inflammed synovium lining the joint cartilage
c. An etiology of a wear and tear process on the joints
d. Being clinically worse in the evening than in the morning
b. Finding a layer of inflammed synovium lining the joint cartilage
Multiple myeloma is a malignant tumor derived from:

a. Chondrogenic tissue
b. Osteoblasts
c. Plasma cells
d. Myeloblasts
c. Plasma cells
The malignant tumor derived from adipose tissue is known as:

a. Rhabdomysarcoma
b. Leiomyosarcoma
c. Chondrosarcoma
d. Liposarcoma
d. Liposarcoma
A 70 year old man presents with some limitation and pain in the left hip. He has otherwise been in good health. This is most likely due to:

a. Infectious arthritis
b. Gouty arthritis
c. Degenerative osteoarthritis
d. Rheumatoid arthritis
c. Degenerative osteoarthritis
Bone in rickets is poorly supportive and deformities and fractures commonly occur due to:

a. Failure of formation of osteoid
b. Connective tissue formed is poorly supportive
c. Failure of mineralization of osteoid
d. Deficient formation of cartilaginous matrix
c. Failure of mineralization of osteoid
Degenerative osteoarthritis:

a. Is much more frequently seen in women than in men
b. Affects small joints predominantly
c. Is histologically associated with formation of a "pannus"
d. Is histologically associated with erosion of articular cartilage
d. Is histologically associated with erosion of articular cartilage
Which of the following is not true about acute osteomyelitis of a long bone:

a. Is usually an infection of older adults
b. Is often caused by staphylococcus
c. Is usually accompanied by fever, bacteremia, bone pain, and swelling
d. Usually responds to antibiotics and surgical drainage
a. Is usually an infection of older adults
A malignant tumor affecting the femur of an adolescent male is likely to be:

a. Chondrosarcoma
b. Osteosarcoma
c. Chondroma
b. Osteosarcoma
The most common neoplasm found in bone is:

a. Metastatic - from distant tissue
b. Chondrosarcoma
c. Osteogenic sarcoma
d. Ewing's sarcoma
a. Metastatic - from distant tissue
Joint ankylosis in rheumatoid arthritis is secondary to:

a. Loss of cartilage with replacement by subchondral bone
b. Elimination of subchondral bone
c. Fibrous replacement of pannus
d. Loss of articular cartilage with formation of osteophytes osteoma
Joint ankylosis in rheumatoid arthritis is secondary to:

a. Loss of cartilage with replacement by subchondral bone
b. Elimination of subchondral bone
c. Fibrous replacement of pannus
All but which one of the following tumors tend to occur in the early decades of life:

a. Osteogenic sarcoma
b. Multiple myeloma
c. Osteoid osteoma
d. Ewing's sarcoma
b. Multiple myeloma
A critical concentration of calcium must be maintained in the peripheral blood. Hypocalcemia triggers:

a. Amount of calcium removed from the bone
b. Increased amount of calcium added to the bone
c. Increased formation of collagen
d. Proliferation of osteoclasts
a. Amount of calcium removed from the bone
A malignant tumor of skeletal muscle seen predominantly in infancy and early childhood is:

a. Fibrosarcoma
b. Rhabdomyosarcoma
c. Liposarcoma
d. Malignant fibrous histiocytoma
b. Rhabdomyosarcoma
What is the function of osteoclasts:

a. Responsible for bone destruction/resorption
b. Responsible for bone formation
c. Both
d. Neither
a. Responsible for bone destruction/resorption