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27 Cards in this Set

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What are the 4 main seronegative spondyloarthropathies?
Ankylosing Spondylitis (AS)

Reiter's Syndrome (reactive arthritis)

Psoriatic Arthritis

Arthritis of Inflammatory Bowel Disease
seronegative spondyloarthropathies are associated with
extraarticular manifestations
(psoriasis, iritis, aortic incompetence, apical pulmonary fibrosis)
what are the extraarticular manifestations of seronegative spondyloarthropathies?
psoriasis, iritis, aortic incompetence, apical pulmonary fibrosis
What are the genetic association for seronegative spondyloarthropathies?
HLA B27 +ve but RF -ve
Epidemiology of Ankylosing Spondylitis?
Onset: late adolescent, early adulthood

Males >> Females

White

Genetic marker HLA-B27~ 90%
Triad of Reiter's Syndrome
Conjunctivitis

Arthritis

Nongonococcal urethritis
Epidemiology of Reiter's Syndrome?
Males >> females

Organisms → Chlamydia, Campylobacter, Yersinia, Shigella, Salmonella

White

Associated with HIV
what is the prevalence of psoriatic arthritis in psoriasis?
5-7%
what is the M:F preponderance of psoriatic arthritis?
M=F
what is the age of onset of psoriatic arthritis?
30-55 years
What are the genetic marker for psoriatic arthritis?
HLA-B27
clinical presentation of psoriasis
Psoriatic skin lesions—erythematous, silvery scales

Auspitz sign—gentle scraping of the lesions results in pinpoint bleeding

extensor surfaces

Nail pitting
Which conditions?
symmetrical small joint polyarthralgia
RA
SLE
Which conditions?
asymmetrical small & large joint polyarthralgia
psoriatic arthritis
Which conditions?
asymmetrical lower limb polyarthralgia
reactive arthritis
Dactylitis (sausage digits) is present in
psoriatic & reactive arthritis
severity of polyarthralgia is best determined by
duration of morning stiffness
what extra-articular features are present in inflammatory spondyloarthropathy?
iritis
inflammatory back pain
asymmetrical lower limb arthritis
what extra-articular features are present in SLE?
raynaud's
malar rash
serositis
proteinuria
what extra-articular features are present in psoriatic arthritis?
scaly rash (psoriasis)
dactylitis
nail pitting
what are the xray findings seen in OA?
joint space narrowing
osteophytes
subchondral sclerosis (increased bone formation around the joint)
subchondral cyst
soft swellings are likely due to
fluid
synovium
hard swellings are likely due to
bone
tophi
CAUSES of carpal tunnel syndrome
overuse / idiopathic
pregnancy & obesity
RA & gout
diabetes, hypothyroid, acromegaly
amyloidosis
Ottawa Knee Rule:
A knee x-ray series is only required for knee injury patients with?
age ≥ 55
isolated patella tenderness
head of fibula tenderness
inability to flex to 90°
inability to bear weight immediately and for 4 steps (transfer weight twice)
Ottawa Ankle Rule:
An ankle x-ray series is only required if
Ottawa Ankle Rule:
A foot x-ray series is only required if
there is any pain in the midfoot zone
+
bone tenderness at base of 5th metatarsal
OR
bone tenderness at navicular
OR
inability to bear weight both immediately & in ED