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16 Cards in this Set
- Front
- Back
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Anti-double stranded -DNA antibody
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SLE (high specificity, low sensitivity)
(pt likely will get lupus nephritis & indicator of disease activity) |
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Anti-Smith
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SLE (high specificity, low sensitivity)
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Anti-nucular antibodies (ANA)
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- SLE (high sensitivity, low specificity)
- Sjogren's, scleroderma etc. - Can be found in 'normal' patients |
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Anti-histone antibodies
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Drug-induced lupus
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Anti Ro (SSA)
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- Sjogren
- Neonatal lupus (cause congenital heart block) - 3% of ANA-negative lupus |
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Anti-LA (SSB)
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Sjogren
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Anti-centromere
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CREST syndrome
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Anti-RNP
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Mixed connective tissue disease
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Postive C-ANCA
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Wegner's
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- Rheumatoid arthritis
- Splenomegaly - Neuropenia (may develop grand positive infections) |
Felty's Syndrome
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- Pre-existing occupational lung disease (pneumaconiosis)
- Rheumaoid nodules in the lung |
Caplan's syndrome
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What is the major complication of RA associate with neck pain, radicular pain of C1, C2 (parastbesia of hans & feet)?
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Atlantoaxial subluxation - can cause paraplegia, quadriplegis,
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We have RA patient who is going for a routine hernia opp under GA what key investigation must we do in our anathestic assessment?
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Radiology of the cervical spine to look for atlantoaxial subluxation
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What drugs are commonly associated with drug induced lupus?
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- Tetracyclines (antibiotic)
- Hydralazine (anti-HBP) - Procainamide (anti-arrhythmic) - Isoniazid (TB) - Chlorpromazine (anti-psychotic) - Methyldopa - Phenytonin (anti-epileptic) - Quinidine (anti-arrthymic) |
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36yrs old women presents with because 'her skin feels thight', painful discolored fingertips with exposure to cold. High BP, elevated creatinine
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Scleroderma with renal involvement
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Spondyloarthropathy with conjunctivitis & arthritis
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Reiter's syndrome
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