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29 Cards in this Set
- Front
- Back
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intermediate onset/doa
names? ROA? |
NPH- Its no protamine hell
Lente -SC only |
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rapid onset
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reg. insulin
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ultra rapid
which diff? |
LAG
-lispro -aspart -glulisine- not IV! |
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Intermediate w/ extended release
how each one do it? |
glargine-microprecitates
determir-fatty attchment both peakless |
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GLP-1 receptor agonist
hypo causin? mech? serious SE |
LE GLP-1
Exenatide Liraglutide -not hypoglycemical up insulin secretion -slow gasstric emptying -down glucagon -w. loss -pancreatitis |
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dipetidyl peptidase 4 inhibitors
hypo causin? mech? serious SE |
D.P. inhibited by Sexy Sox
-Sitaglipin -Saxagliptin -not w/ insulin -delay gastric emptying -pancreatitis |
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Biguanides
hypo causin? mech? serious SE |
big form
-metaformin not hypo -inhibit gluconeogensis -up insulin sen. -less absorb intestines possible lactic acidosis |
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TZD
hypo causin? mech? serious SE |
'Glitazones' TZD-RP
-not hypo -up insulin sen. (up GLUT4 trans.) -depends on insulin to work -w. gain -no prego -2 month full efftect |
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1st gen sulfa
hypo causin? mech? serious SE |
chlorpropamide
-hypo -close K channel ... insulin! -down glucagon -up insulin effects -dermatological -nausea -w. gain (water reten) SIADH |
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2nd gen sulfa
hypo causin? mech? serious SE |
'Gly, glee, glu, glee' (first 2 maybe BID)
-glyburide -glipizide -glucotrol XL -glimepiride |
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Meglinitides
hypo causin? mech? serious SE |
'glinides'
Mean Repo Noob -Repaglinide -Nateglinide -hypo -blocks K channel -w. gain |
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Amylin Agonist
hypo causin? mech? serious SE |
AA's pee
-Pramlintide (symlin) -slow gastric empty -increase satiety -down postmeal glucagon -w. loss |
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Alpha Glucosidase Inhibitors
hypo causin? mech? serious SE |
A gas inhibitor - a must
-Acarbose -Miglitol -not hypo -delay digestion carb and glu (inhibit glucsidase comp.) -take first bite |
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Hypothyriodism replacement
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Liothyroinine- T3
-Cytonel -Triostat Liotrix(ratio) -T4:T3 Levothyroxine - syn T4 -synthroid -levothyroid e before i, specially for the thy |
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Propanolol
-for? mech? |
hyperthyroidism
thyroid storm -inhibit T4->T3 |
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Thionamides
mech? SE? |
-PTU
-Methimazole-10x potent -inhibit iodine oxidation(thyriod peroxidase) -delayed onset -PTU for storm -rare agranulocytosis -dermatological |
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Radioactive I
mech? SE? |
B emission
no prego -can later have hpoythyriodism |
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Anions inhibitors
mech? SE? |
Perchlorate
Thiocynates -compete for I uptake -Perchlorate possible aplastic anemia |
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Iodides
mech? SE? |
Lugols
Sat. KI inhibit T. hormone release cuz high levels -presurgery -no prego -iodism(met. taste) -edema -dermatological hemorage |
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Iodinated contrast medium
mech? SE? |
-diatrazol
-iohexol inhibit T4 to T3 in main areas |
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partial Thyroidectomy
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nooobs!!!!!!!!!!!!!
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thyriod storm use wut?
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PTU
Propranolol K iodide iodine contrast media hydrocortisone -should have back norm 24-48 h |
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Growth Hormone-Releasing Hormone (GHRH)
from? effects? inhibitors? |
hypothalamus
-release GH in pituitary inhibited somatostatin |
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somatostatin
from? effects? used? |
hypothalamus (also pancreas, retina, GI)
-inhibit release GH, insulin, glucagon(more than insulin) -syn. only, human useless -used for various crap and has various side effects |
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GH
growth hormone from effects uses |
anterior pituitary
growth mostly, like insulin at first then opposite used before epitheal plates close ah other stuff |
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Myxedema (Gulls)
hypo/ hyper? symp? |
hypo
can go into coma -CO2 retention, decreased resp. response -fluid/ electrolyte imbalance -hypothermia |
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Cretinism
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insuff. thyroid hormones in infants
-end up retarded dwarfs -endemic or congenital treat w/ T4 |
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Graves
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autoimmune TSh stim body
hyper exophthalmos-big eyeballs symp. think increase metab |
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Plummers disease
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graves only with growth nodule
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