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17 Cards in this Set
- Front
- Back
Lung volumes
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-RV – after max expiration
-ERV – breathable after nl expiration (amt left after nl expiration – RV) -TV – in/out w/ nl breathing -IRV – max inspiration – TV -VC – all but RV (breathable)…ERV+TV+IRV -FRC – after nl expiration…RV+ERV -IC – max breath…IRV+TV -TLC – lung vol…RV+ERV+TV+IRV |
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Phys dead space
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Vt*(PaCO2-PeCO2)/PaCO2
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Dissolved O2
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PO2*solubility
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PaO2 factors
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PAO2 (and thus PCO2, PIO2), A-a gradient
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O2 content
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O2binding*Sat + dissolved O2(PaO2?)
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O2binding
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maximal of O2 bound to Hb at 100% sat
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Sat
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%heme-sites bound by O2 on a given Hb
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Hypoxia/O2 delivery
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CO*O2content
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Alveolar gas equation
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PAO2 = PIO2 – PACO2/R
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Collapsing pressure
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2T/r
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Surfactant fxn
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Increase compliance
↓tension (↓collapsing pressure of alveoli) |
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Major site of airway resistance
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Medium bronchioles
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Models of perfusion-limited vs. diffusion limited
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perfusion-limited – equilibrates early (limited by any dead space)
-N2O -O2 diffusion-limited – never equilibrates -CO -O2 during exercise |
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Why HbF left shift
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Does not bind 2,3 BPG as well
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3 forms of CO2 in blood
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Dissolved
Bound to Hb HCO3 |
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4 changes w/ Exercise
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↑ Ventilation
↑Pulm blood flow/Cardiac Output Even V/Q Unchanged PaO2/PaCO2 |
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5 changes w/ High Altitude
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↓PAO2 (<760?)
respiratory alkalosis EPO Hb ↑2,3 BPG Pulm vasoconstriction ( ↑PA pressure LVH) |