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22 Cards in this Set
- Front
- Back
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Upper respiratory infection(URI)
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Colds, croup(Laryngotracheobronchitis)
Usually self-limiting |
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Lower respiratory infection
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Sever than upper respiratory:
Pneumonia, bronchitis, bronchiolitis Often require specific treatment and hospitalization |
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What is the transmission of Respiratory disease
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Droplet on mucous membranes
Aerosol |
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What are characteristics of family Paramyxoviridae
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Neative stranded RNA
roune-to-pleomorphic, helical nucleocapsid, enveloped |
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What are the charactersitcis of Genome Paramyxoviridae
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15-20kb
6-10 genes w/ 8-11 proteins(P gene w/ > ORF) |
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Paramyxovirus is primarily desease of ??
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Chileren
Measles, Mumps Some viruses/diseases know since antiquity. |
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Paraxyxo stable in environment?
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NO
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Describe the subfamily of Paramyxo
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1. Morbillivirus
2. Rubulavirus 3. Respirovirus 4. Henipavirus |
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What are the transmission and distribution of Henipavirus
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Transmission: Body fluids? Airborn?
Distribution; Australia, Asia, Africa? |
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Describe the subfamily of Pnemoviridae
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1 Pneumovirus
2 Metapneumovirus |
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What are the transmission and distribution of pnemoviridae
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Transmission; Airborn
Distribution; World wide |
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what is only human pathogen of genus Morbillivirus
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Measles
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Where does measles virus reside in infected person
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Mucus of the nose and throat
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What was describe "more dreaded than smallpox"?
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measles in the 10th century AD
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what % susceptability is measles
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90% of close contact
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How many days for transmission of measles virus
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4 before rash to 4 days after onset of rash
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Infectious on contamination surfaces?
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Yes, up to two hours
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Prior to vaccine, what was infection rate?
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Almost universal
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How high is measles mortality today?
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one million children/ year
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What is the only reservoir of measles
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human
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Does wild type infection give life-long immunity
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Yes
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Minimi pop size to maintain measles virus in nature
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~500,000 w/ > 16.000 surviving newborns/year
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