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33 Cards in this Set

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  • Back
What form is available for long acting beta agonists?
DPI
Name the 4 long acting beta-2 agonists
Salmetrol
Fluticasone/Salmetrol
Formoterol
Budesonide/Formoterol
In which patients should you be careful about using anticholinergic respiratory meds?
BPH
Glaucoma
What are the side effects of anticholinergic inhalers?
dry mouth
pharyngeal irritation
urinary retention
increased intraocular press.
What agent (besides albuterol) is first line for pt w/persistent asthma?
inhaled steroid
What does persistant asthma mean?
symptoms at least twice per week
Which drug must you educate pt to rinse their mouth after using?
inhaled steroids (to prevent dysphonia and thrush)
Name the inhaled steroids
Beclomethasone
Budesonide
Flunisolide
Fluticasone
Triacinolone
Mometatasone
Which inhaled steroids are available in inhalers, not DPI?
Beclomethasone
Fluticasone
Which asthma drugs have no effect on smooth muscle tone in the airway?
Cromolyn and Nedocromil
Which patients would maybe be okay candidates for cromolyn?
exercise induced asthma or allergic asthma (need to use as prevention)
Why is cromolyn used so much in children?
minimally absorbed --> minimal side effects
What asthma drug is the most potent bronchodilator?
theophylline
What peak plasma levels of theophylline result in seizures and arrhythmias?
>40mcg/mL
How long do you have to wait to escalate the theophylline dose?
3 days
What are the three risk factors for decreased theophylline clearance?
1. <1 or >60
2. concurrent disease
3. use of 3A4 inhibitors or d/c of 3A4 inducers
What are the leukotriene modifiers?
Zilueton
Zafirlikast
Montelukast
Which leukotriene modifier should not be used?
Zilueton
Which Leukotriene modifier has fewer CYP interactions and is better tolerated?
Montelukast
What does Zileuton cause?
hepatotoxicity and agranulocytosis
What is the Anti-IgE Aby that is given subQ to prevent response to allergens?
Omalizumab
What is Omalizumab approved for?
moderate-severe persistent asthma w/allergic componenent and poor control
What must be tested before prescribing Omalizumab?
IgE levels
Which long acting beta agonist is preferred in pregnancy?
salmetrol
What drug might you consider for major night component to asthma?
theophylline
When should pt w/hx of tobacco use have spirometry?
age 45
Name 3 inhaled short acting beta agonists?
Albuterol
Levalbuterol
Pirbuterol
Do you need to give more or less beta agonist if using nebulizer?
more
which beta agonists come in pill form?
albuterol
metaproterenol
terbutaline
What is the MDI or nebulized anticholinergic called?
Atrovent
What is ipratropium + albuterol called if it is in nebulized form?
Duoneb
What is ipratropium+albuterol called if it is MDI?
Combivent
Which asthma drug is used off label for asthma tx as add-on tx to inhaled steroids?
Ipratropium