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19 Cards in this Set
- Front
- Back
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Diphenydramine Dimenhydrinate Chlorpheniramine |
Reversible H1 receptor blockers (1st gen) Use: allergy, motion sickness, sleep aid S/e: sedation, anti-muscarinic, anti-alpha adrenergic |
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Loratadine Fexofenadine Desloratadine Cetirizine |
Reversible H1 receptor blockers (2nd gen) Use: Allergy S/e: way less sedating because cannot enter CNS |
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Guaifenesin
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Thins out respiratory secretion without suppressing cough
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N-acetylcysteine
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Disrupts disulfide bonds in mucus Use: COPD ***give for acetaminophen overdose*** |
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Dextromethorphan
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Codeine analog. Antagonizes NMDA glutamate receptos. S/e: mild opiate effect Reverse with naloxone Watch out for 5ht syndrome |
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Pseudoephedrine (makes meth) Phenylephrine |
a-adrenergic agonist used for nasal decongestants use: reduce hyperemia, edema and nasal congestion, open Eustachian tubes S/e: HIGH BLOOD PRESSURE |
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Bosentan
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Antagonizes ENdothelin-1 to block pulmonary VCx Use: Pulmonary HTN S/e: liver toxicity |
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Sildenafil
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Inhibitor of PDE5 to increase duration of NO effect-> VDx pulmonary bv Use: Pulmonary HTN and ED |
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Epoprostenol Iloprost |
PGI-2!! Direct VDx on lungs are arteriesS/e: flushing, jaw pain
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Albuterol
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Short acting B2 agonist that relaxes bronchial smc -good for acute asthma attack |
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Salmeterol Formoterol |
Long acting B2 agonist for asthma prophylaxis S/e: TREMOR, arrhythmia |
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Fluticasone, budesonide
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Inhaled corticosteroid that block synthesis of all cytokines -block NFKB, thereby blocking production of TNF2. -First line for chronic asthma |
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Ipratropium
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Blocks muscarinic receptors to prevent bronchoconstriction. Long-acting Use: COPD and asthma |
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Montelukast Zafirlukast |
Block LT receptor CysLT1 Use: aspirin-induced asthma |
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Zileuton
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5-Lipoxygenase pathway inhibitor that blocks conversion of AA to LT -s/e: liver tox |
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Omalizumab
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Binds to IgE in the serum to block IgE from binding to FcERI -used: allergic asthma with high IgE if asthma is resistant to inhaled steroid and long-acting B2 agonist |
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theophylline
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Methylxanthine= theophylline MoA: Blocks PDE to increase cAMP. S/e: tremor, seizure, insomnia, low bp, high HR, arrhythmias due to narrow TI S/e: blocks adenosine action |
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Methocholine
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M3 agonist that helps diagnose asthma
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Cromoglycates, neclocromil
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Block Hitsamine release by preventing MC from degranulating use: prevent acute attacks but do not treat current attacks -seasonal asthma -aspirin hypersensitivity-exercise asthma
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