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18 Cards in this Set
- Front
- Back
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If you wanted non-drowsy allergy relief, which 3 drugs fit the profile?
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2nd generation H1 blockers: loratadine, fexofenadine, desloratadine
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Which antihistamines are sedating, antimuscarinic, and anti-alpha adrenergic?
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1st generation: diphenhydramine, dimenhydrinate, chlorpheniramine
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Diphenhydramine =
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1st generation H1 blocker
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Dimenhydrinate =
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1st generation H1 blocker
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Chlorpheniramine =
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1st generation H1 blocker
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Loratadine =
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2nd generation H1 blocker
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Fexofenadine =
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2nd generation H1 blocker
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Desloratadine =
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2nd generation H1 blocker
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Isoproterenol =
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nonspecific beta agonist - bronchodilator, but also get tachycardia from beta 1 effect
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Albuterol =
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beta 2 agonist - acute asthma
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Salmeterol =
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beta 2 agonist - long acting prophylaxis for asthma; side effects tremor & arrhythmia
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Theophylline =
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bronchodilator - narrow therapeutic index because cardio/neurotoxicity
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Ipratropium =
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muscarininc antagonist --> bronchodilation
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Cromolyn sodium =
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prevent degranulation of mast cells - only PROPHYLAXIS use in asthma
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Beclomethasone, prednisone =
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corticosteroids, 1st line for chronic asthma - inactivate NF-KB so do not make TNFa or other inflammatory cytokines
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Zileuton =
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block lipooxygenase so do not make LT's
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Zafirlukast, montelukast =
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block LT receptors
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Which asthma drug is thought to inactive phosphodiesterase and thereby inc. levels of cAMP --> smooth muscle relaxation?
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Theophylline (a methylxanthine)
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