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18 Cards in this Set

  • Front
  • Back
If you wanted non-drowsy allergy relief, which 3 drugs fit the profile?
2nd generation H1 blockers: loratadine, fexofenadine, desloratadine
Which antihistamines are sedating, antimuscarinic, and anti-alpha adrenergic?
1st generation: diphenhydramine, dimenhydrinate, chlorpheniramine
Diphenhydramine =
1st generation H1 blocker
Dimenhydrinate =
1st generation H1 blocker
Chlorpheniramine =
1st generation H1 blocker
Loratadine =
2nd generation H1 blocker
Fexofenadine =
2nd generation H1 blocker
Desloratadine =
2nd generation H1 blocker
Isoproterenol =
nonspecific beta agonist - bronchodilator, but also get tachycardia from beta 1 effect
Albuterol =
beta 2 agonist - acute asthma
Salmeterol =
beta 2 agonist - long acting prophylaxis for asthma; side effects tremor & arrhythmia
Theophylline =
bronchodilator - narrow therapeutic index because cardio/neurotoxicity
Ipratropium =
muscarininc antagonist --> bronchodilation
Cromolyn sodium =
prevent degranulation of mast cells - only PROPHYLAXIS use in asthma
Beclomethasone, prednisone =
corticosteroids, 1st line for chronic asthma - inactivate NF-KB so do not make TNFa or other inflammatory cytokines
Zileuton =
block lipooxygenase so do not make LT's
Zafirlukast, montelukast =
block LT receptors
Which asthma drug is thought to inactive phosphodiesterase and thereby inc. levels of cAMP --> smooth muscle relaxation?
Theophylline (a methylxanthine)