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21 Cards in this Set

  • Front
  • Back
What are the main functions of the respiratory system?
gas exchange
metabolism - angiotensin
Synthesis - surfactant
Filtration
Reservoir of blood
With inspiration and expiration, which is active and which is passive. What species do we see active inspiration and expiration?
inspiration = active
expiration = inactive

birds have both active inspiration and expiration
What gas has a direct relationship with inspiration?
CO2
What are the peripheral controllers of respiration?
Carotid and aortic bodies that are sensitive to PO2
What does the upper airway consist of?
Conducting zone?
The transitional and respiratory zone?
nose to pharynx

trachea, bronchi, bronchioles

respiratory bronchiole, alveolar duct, alveolar sac, alveoli
What is the bronchiole circulation?
Pulmonary circulation?
from left side of the heart - metabolic needs

from right side of the heart - gas exchange
What nerve innervates the diaphragm?
Phrenic
What happens in gas exchange?
-Simple diffusion (CO2 diffuses more easily than O2)
-Partial pressure gradient
-Fick's law of diffusion
With the Hb dissociation curve what happens during a "left shift"? With H+, PCO2 & temp?
When does this happen?
Hb has more affinity for O2
H+, PCO2 & temp decrease
During inspiration
With the Hb dissociation curve what happens during a "right shift"? With H+, PCO2 & temp?
When does this happen?
Hb has less affinity for O2
H+, PCO2, and temp increase
When air reaches the tissue, cause you want it to leave the Hb
In what form is largest percentage of CO2 carried in the blood?
Bicarbonate
What is the definition of alveolar dead space?
An alveoli which is ventilated but NOT perfused
What is the definition of a shunt? What is an example?
An alveoli which is well perfused but NOT ventilated
ex. collapsed lung
What are the five causes of hypoxaemia?
1 Low inspired O2
2 Hypoventilation
3 Ventilation perfusion mismatch
4 Shunt
5 Diffusion impairment
Is an extrathroacic airway disease louder during inspiration or expiration? Intrathoracic?
Inspiration
Expiration
What are the three types of lung pathologies? (ROV)
1) Obstructive (airway)
2) Restrictive (lungs can't expand)
3) Vascular disease
What are three examples of obstructive diseases?
-Asthma
-COPD (emphysema, chronic bronchitis)
-Localized airway obstruction
What is the pathogenesis of asthma? Is there bronchoconstriction with bronchitis?
Airway edema -> hypersecretion of mucus -> inflammation -> bronchoconstriction
No
What are some examples of restrictive diseases?
Pneumothorax, pleural effusion, pleural thickening
What are examples of vascular diseases?
Pulmonary edema, embolism and hypertension
Central control of breathing occurs in what part of the brain? What is the brain sensitive to? What is this influenced by?
Medulla
Hydrogen ions
PCO2