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34 Cards in this Set
- Front
- Back
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Normal FEV1/FVC ratio =
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0.8
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Amount PaCO2 increases during Apnea: 1st minute, subsequent minutes
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1st minute: 6mm Hg
2nd minute: 3-4 mm Hg |
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O2 requirement for Adult in GA
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3-4 ml/kg/min
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O2 requirement for Newborn in GA
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7-9 ml/kg/min
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TV
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500 ml (6-8 ml/kg)
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IRV
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3000 ml
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ERV
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1200 ml
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RV
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1200 ml
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FRC
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2400 ml (ERV + RV)
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IC
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3500 ml (IRV + TV)
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VC
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4900 ml (60 - 70 ml /kg)
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TLC
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5900 ml
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Increase in Minute Ventilation per increase in PaCO2
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1-3 L/min/mmHg PaCO2
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Adult P50 for Hb
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26
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Increase in PH / 10 mmHg increase in PaCo2
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0.08 / 10 mm Hg PaCO2
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Δ [HCO3] / Δ PCO2 <40 =
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0.5 meQ/L [HCO3] / mmHg PaCO2
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Δ PaCO2 / Δ [HCO3] <24 =
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1 mmHg PaCO2 / 1 mEq /L [HCO3]
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Δ pH / Δ [HCO3] <24 =
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0.015 / 1 mEq / L
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Δ [K+] / Δ pH
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-0.5 meQ / 0.08 units pH
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Compensetory Responses to Resp Alkylosis (3)
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1) Shift in HCO3 - CO2 equilib --> increase CO2
2) Increase PFK activity --> increase glycolysis --> increased lactic acid production 3) Decreased reabsorption of HCO3 in proximal and distal renal tubules. |
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Goals in management of AFib (3)
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1) Control ventricular rate
2) Asses anticoag needs 3) Return to Sinus Rhythm |
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Causes of Right Shift OxyHb curve (7)
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1) Acidosis
2) Increased PaCO2 3) Increased Temp 4) Increased 2,3 DPG 5) Pregnancy 6) Sickle Cell Hb 7) Thallasemia |
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Causes of Left Shift OxyHb curve (7)
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1) Alkylosis
2) Decreased PaCO2 3) Decreased 2,3 DPG 4) Fetal Hb 5) Carboxy Hb 6) Meth Hb 7) Sulf Hb |
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P50 Fetal Hb
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31 mm Hg
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Key signs of CO poisoning (3)
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1) Decreased SaO2 % on ABG with nl PaO2
2) Normal finger Pulse Ox 3) Left shift OxyHb curve |
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% of O2 consumption towards work of breathing =
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2%
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Adult anatomic dead space =
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2 ml/kg
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Signs of Cyanide toxicity from Nitroprusside (3)
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1) Tachyphalaxis
2) Metabolic Acidosis 3) Increased SvO2 |
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Treatment for Cyanide toxicity (2)
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1) Sodium Thiosulfate 150 mg IV over 15 min
2) For severe tox: Sodium Nitrate 5 mg/kg |
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Adverse effects of Alkylosis (8)
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1) Coronary Artery Vasoconstriction
2) Decreased Cerebral Blood Flow 3) CNS excitation 4) Dysrythmias 5) Increased Airway Resistance 6) Left Shift OxyHb curve 7) Decreased [K+] 8) Decreased [Ca2+] |
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Adverse effects of Acidosis (6)
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1) CNS Depression
2) Dysrythmias 3) Cardiac Depression 4) Pulmonary HTN 5) Increased [K+] 6) Hypovolemia |
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Causes of Normal Anion Gap Acidosis (6)
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1) Pancreatic-duodenal fistula
2) Ureteral - enteric fistula 3) RTA 4) Hypercholremia 5) Diarrhea 6) Drugs (Acetazolamide) |
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Causes of Increased Pulmonary Vascular Resistance (6)
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1) Acidosis
2) Increased CO2 3) Hypoxia 4) Atalectasis 5) Increased Hct 6) Sympathetic Stimulation |
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Causes of Methhemoglobinemia (3)
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1) O-toludine
2) Sodium Nitroprusside 3) Nitroglycerin |
