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3 Cards in this Set
- Front
- Back
Branching of duct -- mesenchyme/mesoderm
FGF10 TGF-b epimorphin |
FGF10: cause TIP of lung bud to grow via epithelial mitosis
TGF-b (induced by Shh): lay down collage & fibronectin epimorphin: signals location of BASAL region; determines the polarity of the cell Tenascin/Syndecan: sheets/straight tubes > globular, branching |
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Functionality of tissue -- epithelium/endo
Shh BMP4 VEGF |
Shh & BMP4 (secreted at the tip): inhibit GFG10-induced growth
Shh: induce mesenchyme to produce TGF-b after cessation of growth VEGF: induce capillary growth |
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d
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d
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