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3 Cards in this Set

  • Front
  • Back
Branching of duct -- mesenchyme/mesoderm

FGF10
TGF-b
epimorphin
FGF10: cause TIP of lung bud to grow via epithelial mitosis

TGF-b (induced by Shh): lay down collage & fibronectin

epimorphin: signals location of BASAL region; determines the polarity of the cell

Tenascin/Syndecan: sheets/straight tubes > globular, branching
Functionality of tissue -- epithelium/endo

Shh
BMP4
VEGF
Shh & BMP4 (secreted at the tip): inhibit GFG10-induced growth
Shh: induce mesenchyme to produce TGF-b after cessation of growth

VEGF: induce capillary growth
d
d