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19 Cards in this Set
- Front
- Back
- 3rd side (hint)
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diphenhydramine
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reversible inhibitor of H1 receptor, first generation
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Use: allergy, motion sickness, sleep aid
Toxicity: sedation, antimuscarinic, anti-alpha cholinergic |
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dimenhydrinate
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reversible inhibitor of H1 receptor, first generation
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Use: allergy, motion sickness, sleep aid
Toxicity: sedation, antimuscarinic, anti-alpha cholinergic |
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chlorpheniramine
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reversible inhibitor of H1 receptor, first generation
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Use: allergy, motion sickness, sleep aid
Toxicity: sedation, antimuscarinic, anti-alpha cholinergic |
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loratadine
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reversible inhibitor of H1 receptor, second generation
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Use: Allergy
Toxicity: less sedation than 1st gen because of decreased CNS entry |
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fexofenadine
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reversible inhibitor of H1 receptor, second generation
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Use: Allergy
Toxicity: less sedation than 1st gen because of decreased CNS entry |
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desloratadine
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reversible inhibitor of H1 receptor, second generation
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Use: Allergy
Toxicity: less sedation than 1st gen because of decreased CNS entry |
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cetirizine
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reversible inhibitor of H1 receptor, second generation
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Use: Allergy
Toxicity: less sedation than 1st gen because of decreased CNS entry |
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isoprotenenol
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beta 2 agonist relaxes bronchial smooth muscle
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use: asthma
Toxicity: beta 1 activity |
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albuterol
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beta 2 agonist
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use: acute exacerbation
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salmeretol
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beta 2 agonist, long acting
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use: asthma prophylaxis
Toxicity: tremor and arrythmia |
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Theophylline
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methylxanthine, cuases bronchodilation by inhibiting phosphodiesterase
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toxicity: narrow therapeutic window with cardiotoxicity and neruotoxicity; metabolized by P450, blocks actions of adenosine
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ipratorium
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blocks muscarinic receptors and prevents broncho-constriction
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use: asthma and COPD
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cromolyn sodium
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prevents release of mediators from mast cells
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use: prophylaxis or asthma
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corticosteroids
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beclomethasone, prednisone inhibit synthesis of cytokines and inactiate NFkB which decreases TNF alpha
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use: first line for chronic asthma
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zileuton
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5-lipoxygenase pathway inhibitor blocks concersion of arachodonic acid to LKTs
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Zafirukast, montelukast
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block LKT receptors
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use: aspirin induced asthma
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Guaifensin
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expectant-removes excess sputum and does not suppress cough reflex
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N-acetylcysteine
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mucolytic, loosens mucous plus in CF patients
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bosentan
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antagonize endothelin-1 receptor and decrease pulmonary vascular 1 resistance
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Use: pulmonary hypertension
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