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14 Cards in this Set

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  • Back

What is Acute Mountain Sickness?

defined as the presence of headache in an unacclimatized person who has recently arrived at an altitude of 2500 m (8202 ft), plus the presence of one or more of the following: GI symptoms (anorexia, nausea, or vomiting), insomnia, dizziness, lassitude, or fatigue

What is Tx of choice for Acute Mountain Sickness?

Descent; O2

What is recommended initial medical therapy for Acute Mountain Sickness?

Acetazolamide

What is affective in lowering severity of Acute Mountain Sickness?

dexamethasone

What are best ways to prevent Acute Mountain Sickness?

Gradual ascent; allowing time for acclimatization

What are characteristics of Acute Mountain Sickness?

relative hypoventilation, impaired gas exchange, increased sympathetic activity, fluid retention and redistribution, and in moderate to severe AMS, raised intracranial pressure

Patients with which diseases should be counseled on AMS?

obstructive sleep apnea, chronic obstructive pulmonary disease (COPD), asthma, pulmonary hypertension, thromboembolic disease, and others should be screened and counseled about travel to high-altitude destinations prior to travel

DDX for AMS?

Acute psychosis


Anxiety


Diabetic ketoacidosis


Dehydration


Hangover


Hypoglycemia


Hyponatremia


Hypothermia


Ingestion of drugs, toxins, and alcohol


Neoplasms, brain


Stroke


Toxicity, carbon monoxide


Transient ischemic attack

What is the cardinal symptom of AMS?

headache (6-12 hours after ascent)

Acetazolamide should be avoided in:

hepatic disease


pregnancy


sulfa allergy

Alternative to acetazolamide in those with liver/kidney disease:

dexamethasone

Dexamethasone should be avoided in:

pregnant


GI/Peptic ulcer


Side effect of dexamethasone if abruptly discontinued:

depression

What is the severe side of AMS?

1. HACE, which requires hospitalization. HACE is defined as symptoms of AMS plus gait ataxia or mental status changes. HACE may also be defined as gait ataxia and mental status changes regardless of AMS symptoms


2. HAPE is diagnosed in patients with at least 2 of the following signs and symptoms: dyspnea at rest, cough, weakness, decreased exercise performance, chest tightness or congestion and crackles, wheezing, central cyanosis, tachypnea, or tachycardia.