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84 Cards in this Set

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Hypercapnic RF results from an imbalance between?

Ventilatory supply and Ventilatory Demand

Define Ventilatory Supply

The MAXIMUM ventillation (gas flow in and out of lungs) that someone can sustain without developing resp muscle fatigue




When ventilatory demand EXCEEDS vent supply (needing a lot more ventilation to keep Co2 within normal limits)

Define Ventilatory Demand

The amount of VENTILATION (gas) that is needed to keep PaC02 within normal limits

Normally, ventillatory ____ exceeds demand

SUPPLY (people can handle a lot of gas without getting muscle fatigue) Therefore people can exercise great and not have to worry about a huge increase in PaC02




(But not people with COPD, other problems)

Hypercapnia reflects ____ lung dysfunction

Substantial

Hypercapnic RF is sometimes called?

Ventilatory Failure (Primary problem: Respiratory system INABILITY to remove sufficient C02 to maintain NORMAL PaC02.

Hypercapnic RF can ALSO be labeled as?

Acute vs. Chronic

MANY different diseases can cause a limitation in ventilatory supply. The diseases can be grouped into 4 categories. Name them

1) Abormalities of Airways +Alveoli


2) Abnormalities of CNS


3) Abnormalities of Chest Wall


4) Neuromuscular Conditions

People that have airway/alveoli abnormalities are at HIGH risk for Hypercapnic Respiratory Failure because, such conditions result in airflow OBSTRUCTION and air trapping. List some of the conditions (3)

1. Asthma


2. CPOD


3. Cystic Fibrosis

Ultimately, Respiratory muscle fatigue and ventilatory failure occur d/t?

Additional WORK needed to inspire adequate tidal volumes against such increased airway resistance/air trapped within alveoli

A variety of CNS problems may SUPRESS the drive to? Name an example

Breathe ; Overdose of a respiratory depressant drug (opiods, benzodiazepines)




CNS DEPRESSANTS.

CNS depressants DECREASE C02 reactivity in?

Brainstem. (this allows arterial Co2 levels to rise)

Other examples of CNS situations that can cause hypercapnic RF include? (3)

Brainstem infarction, severe head injury (mess with the respiratory center in medulla)


+High level spinal cord injuries




People at risk because the medulla doesn't ALTER the respiratory rate based on a change in PaC02.

Metabolic or structural brain injury resulting in DECREASED or LOSS of consciousness, may interfere with the patient's ability to manage ___ or adequately protect his/her airway

Secretions

Chest wall abnormalities. Several conditions can PREVENT normal movement of the chest wall and LIMIT lung ___

Expansion (Causing PaC02 to build up)




They also limit diaphragmatic movement, therefore gas exchange

List examples of such chest wall abormalities (3)

1) Flail Chest: Fractures prevent rib cage from expanding d/tpain, mechanical restriction, and muscle spasm




2) Kyphoscoliosis: Change in spinal configuration COMPRESSES the lungs and prevents normal expansion of chest wall




3) Obesity: Weight of chest/abdominal contents may limit expansion

Various types of NEUROMUSCULAR conditions/diseases may result in respiratory muscle weakness or PARALYSIS. List examples of those that are unable to maintain adequate PaC02 levels

Muscular Dystrophy, Multiple Sclerosis, Myasthenia Gravis

Why are they at risk?

Respiratory muscles are weakened or paralyzed d/t result of UNDERLYING neuromuscular condition




(Muscle wasting, peripheral nerve damage, prolonged effects of neuromuscular blocking agents, etc)

Neuromuscular disorders may be acquired as a consequence of exposure to?

Toxins (they can interefere with NERVE supply to muscle and lung ventilation)

RF occurs because what things may not be functioning normally?

1) Medulla


2) Chest wall


3) Peripheral Nerves tissue


4) Respiratory Muscles


5) Damage to lung

May be UNABLE to INSPIRE a TIDAL VOLUME, sufficient enough to remove ___ from lungs

C02

Remember that even though Pa02 and PaC02 determine the defintion of RF, the major cause of RF is the lungs inability to meet?

Lungs can't meet the 02 needs of the tissues


(inadequate 02 delivery to tissues, or tissues may not even be able to use the 02 delivered to them) May also occur due to overall stress response and dramatic increases in tissue 02 consumption (if happening too fast)

Tissue 02 delivery is determined by what 2 main things?

Cardiac Output + Amount of 02 carried in hemoglobin

RF can put the patient at GREATER risk, if they have heart problems or anemia. t/f?

True

Failure of 02 use most commonly occurs in?

Septic Shock (While adequate oxygen may be delivered to the tissues, impaired o2 extraction or diffusion limitation is existing at the cellular level) This results in ABNORMALLY HIGH 02 returning in venous blood, because it is not used a the tissue level

What else may interfere with 02 delivery to peripheral tissues?

Acid-Base Alterations ( Ex: Alkalosis and Acidosis)

Clinical Manifestations. RF may develop ____ (minutes or hours) or gradually (several days or longer)

Suddenly

A sudden DECREASE in Pa02 or RAPID increase in PaC02, implies a?

Serious condition (Ex: Asthma patient with severe bronchospasm) Could result in rapid respiratory muscle fatigue, acidemia, and RF (C02 build up)




This happened rapidly, so dangerous

A more GRADUAL change in Pa02 and Pac02 is better tolerated because?

Compensation can occur (Ex: If patient with COPD developed a respiratory infection over several days, and their renal compensation kicked in to minimize change in arterial PH to prevent respiratory acidosis

Manifestations of RF are r/t to the EXTENT of change in Pa02 or PaC02, how rapid the change happened (acute vs chronic), + patients ability to compensate for the change. T/F

True :) Very Important

When the patient's compensatory mechanisms FAIL, ____ occurs

RF

Because clinical manifestations vary, its important to watch for trends in? (3)

1) ABG's


2) Pulse Oximetry


3) Assessment Findings

Frequently, the FIRST indication of RF is a change in the persons?

Mental Status (Not getting enough o2)




(Brain sensitive to variations in 02, C02, and acid-base balance)

Mental status changes occur EARLY, even before the ___ results are obtained

ABG

What behaviors suggest INADEQUATE 02 delivery to the brain and should be FULLY investigated?

1) Restlesness


2) Confusion


3) Agitation


4) Combative Behavior

Manifestations may be PRIMARY OR SECONDARY. Explain the difference between the 2

1) Primary: Arising from the Respiratory System


2) Secondary: Arising from body systems

What are some examples of symptoms that indicate that the heart and lungs are trying to compensate for decreased 02 delivery.

Tachycardia, Tachypnea, Mild Hypertension (to try and deliver more blood/oxygen to the brain. Respirations, trying to breathe in more air and get 02)




May develop due to stress/rise in catecholaime levels

A SEVERE morning HA may suggest that ____ occured during the night. And why?

Hypercapnia




(Hypercapnia causes CEREBRAL vasodilation, increasing cerebral blood flow, and a mild increase in ICP): produces the HA

At night the respiratory rate is slower and the lungs of patients at risk for respiratory failure may remove less?

PaC02



Rapid shallow breaths suggest that tidal volume may be INADEQUATE to remove __ from lungs

C02 (trying to remove excess c02)

____ is an UNRELIABLE indicator of hypoexemia and is a LATE sign of respiratory failure because it doesn't even occur until hypoxemia is super severe =

Pa02 of 45 mm Hg or less

Consequences of Hypoexemia and Hypoxia. Hypoxemia occurs when the amount of 02 in ARTERIAL blood is less than?

The NL value

Normal Pa02 is?

80-100 mm Hg

Hypoxia occurs when the Pa02 falls SUFFICIENTLY to cause signs and symptoms of?

Inadequate Oxygenation



HYPOXEMIA can lead to HYPOXIA if not ___

Corrected

If hypoxia or hypoxemia is SEVERE, the cells can shift from?

Aerobic to ANAEROBIC metabolism

Anaerobic metabolism uses MORE fule+ produces ___ energy

LESS




(Overall less sufficient than aerobic metabolism)

What is the BYPRODUCT of anaerobic respiration?

LACTIC ACID (which is even MORE difficult to remove from the body than C02, because it has to be BUFFERED with Sodium Bicarb)

When the body doesn't have enough sodium bicarb to BUFFER that lactic acid produced by anaerobic metabolism, what can occur? (3)

1) Metabolic ACIDOSIS


2) Tissue and Cellular Dysfunction


3) Cell Death may occur

With anaerobic metabolism, what two elements can fall? (2)

1) BP


2) CO

When anaerobic metabolism is going on and can cause BP+ CO to drop, certain agents may be less effective in that acidotic enviornment. Name two examples of these agents that may be less effective?

1) Vasoactive


2) Inotropic

Hypoxia and metabolic acidosis have ADVERSE effects on?

Vital organs, especially heart and CNS

HTN occurs primarily due to?


Increased stress/Cat response







As Pa02 decreases and acidosis increases, the myocardium becomes DYSFUNCTIONAL and CO may?

Decrease

Along with all the other clinical manifestations, what other 2 symptoms may occur?

Angina, Dysrhythmias

Permanent brain damage can occur if hypoxia is SEVERE and prolonged T/F

True

Renal function may also be impaired, resulting in?

Sodium Retention, Edema, Acute Tubular Necrosis, and uremia




Uremia:a raised level in the blood of urea and other nitrogenous waste compounds that are normally eliminated by the kidneys.

GI system alterations include

Tissue ischemia, increased perm of intestinal wall, + possible migration of bacteria from GI tract into circulation





Patients in RF can have breathing that is either?

1) RAPID and shallow- can lead to resp muscle fatigue


2) SLOWER respirations than normal




(Both patterns predispose the patient to insufficient C02 removal)





A change from a RAPID to a SLOWER rate in a patient with acute respiratory distress (ex: asthma), suggests extreme progression of respiratory muscle fatigue and increased probability of?

Respiratory Arrest

The patient's position is an indication of the effort associated with?

WOB (work of breathing) + effort used for muscle contraction during inhalation to accomplish lung ventilation

What would indicate that the patient is in mild distress?

If the patient is able to lie down

What would indicate that the patient is in moderate distress?

Able to lie down, but prefer to sit

What would indicate that the patient is UNABLE to breathe unless sitting upright?

SEVERE Distress.

Define TRIPOD position- helps to decrease?

Indicative of the client with CPOD, having to sit with arms propped on overhead table, or on knees.




Helps decrease WOB, since propping the arms increases ANTEROPOSTERIOR DIAMETER of chest and changes pressure in the thorax. (or for those with asthma)





Patients may also use what type of breathing to help increase Sa02, due to the fact that it slows respirations, allows more time for exporation, and prevents the small bronchioles from collasping (helps air exchange)

Pursed lip breathing

Another assessment is- How many pillows does the patient need to breathe comfortably, when lying flat. What is this called?

Orthopnea (ex: 1, 2, 3, or 4) , along with how far the patient can walk without having to stop for rest.

The patients ability to speak indicates the severity of the?

Dyspnea

The Inspiratory (I) to Expiratory (E) (I:E) ratio may change, in patients with?

Respiratory distress

Normally, I:E ratio is?

1:2 (expiration is TWICE as long as inspiration)


This could increase up to 1:4, which signifies airflow obstruction




(requiring more time is needed to empty lungs)

May observe retraction:

INWARD movement of the intercostal spaces or supraclavicular area and use of accessory muscles (sternocledio) during inspiration or expiration.


Use of accessory muscles signifies _____ distress. Paradoxic breathing indicates ___ distress

Moderate; Severe.

Normally, the abdomen and chest move ioutward during inhalation, and inward during?

Exhalation

Paradoxic breathing results in? Results from?

The abdomen and the chest moving in the OPPOSITE manner (outward during exhalation, and inward during inspiration)




Results from maximal use of accessory muscles of respiration. Patient may also be diaphoretic from WOB

We need to perform breath sounds to assess the patients baseline breath sounds and note any changes from?

Baseline

Note and document the presence and location of any?

Abnormal Breath Sounds

Crackles- generally heard on?

INSPIRATION (may indicate pulmonary edema)

Rhonchi (generally heard on expiration), may indicate?

additional lung secretions and may be symptomatic of pneumonia or COPD

Absent or diminished breath sounds may indicate?

Atelectasis, pleural effusion, or impaired inspiratory effort and hypoventilation.

Bronchial breath sounds over the lung periphery often indicate?

Lung consolidation from pneumonia

A pleural friction rub may also be heard in the presence of pneumonia that involves the?

Pleura

Diagnostic studies. AFTER physical assessment, the most common dx studies to evaluate resp failure are?

1) Chest X ray


2) ABG Analysis

A chest x ray helps to determine the possible cause of?

Respiratory Failure (Ex: Atelectasis, Pneumonia)

ABGS determine the levels of?

PaC02, Pa02, Bicarbonate, and PH