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22 Cards in this Set

  • Front
  • Back
Fick's Equation
Rate of Diffusion of Oxygen into cells.
What is the percentage of oxygen in the atmosphere?
21%
Partial Pressure of Oxygen decreases with what
Elevation
Mammal Lungs
Organ: Lung
Exchange Surface: Alveoli
Air Flow: Bidirectional
Model: Open Pool
Pump: Thoracic Expansion
Bird Lungs
Organ: Parabronchi
Exchange Surface: Air Capillaries
Air Flow: Unidirectional
Model: Cross Current
Pump: Air Sac Expansion
Fish Gills
Organ: Gills
Exchange Surface: Lamellae
Air Flow: Unidirectional
Model: Counter Current
Pump: Bucco-Opercular Pump
Problems with Gas Exchange in Water
1. Low Oxygen concentration
2. Water is dense compared to air
3. Messes with salt and water balance
Solutions to Gas Exchange Problems in Water
Unidirectional flow, counter current flow of water and blood, ram ventilation
Problems with Gas Exchange in Air
Large amounts of Dead space, lots of branching, open pool
2 Secretions in mammalian lungs
1. Mucus to capture dirt
2. Surfactant to reduce surface tension
Inhalation
Negative pressure in chest
Exhalation
Elastic recoil as muscles relax
Avian Respiration
Air Sacs keep air flow continuous and unidirectional. Parabronchi = Lung. 2 inhalations + 2 exhalations = 1 cycle
Cross Current Gas Exchange
Air Capillaries are perpendicular to the parabronchi for high oxygen extraction
What is the primary information that regulates breathing rate
CO2 concentration in blood. Which is monitored by the medulla. Oxygen concentration is monitored by carotid and aoritc bodies in the blood vessels
Medullary Respiratory Center
Controls Breathing Rate, a small increase in CO2 leads to a large increase in breathing. A large decrease in O2 has a small increase in breathing
Hemoglobin
4 subunits each with a heme molecule. Each heme can bind 1 O2.
Oxygen-Hemoglobin Dissociation Curve
The different in O2 between blood and tissues drives the loading and unloading of O2.
Cooperative Binding
Heme subunits likely bind/release oxygen when another heme is bound/unbound to oxygen

Results in greater O2 delivery
Bohr Shift
Increasing temperature = decrease in pH. Decreasing pH results in a increase of release of O2 from hemoglobin
CO2 Transport and Buffering in the blood
CO2 and H20 is transported as HCO3- in the blood. The extra proton acts as a buffer.
Erythropoietin
Stimulates RBC production in Bone Marrow