Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
21 Cards in this Set
- Front
- Back
|
t/f pharyngitis can be dx clinically
|
false
|
|
|
giving a pt antibiotics with pharyngitis will relieve their symptoms right/
|
nooooo
|
|
|
Clinical manifestations of strep pharyngitis
|
abrupt onset of sore throat
nausea vomitting and above 102.5 fever red edematous pharynx, tonsils small focal or confleunt areas of yellow/gray exudate |
|
|
define scarlet fever
|
grp a strep lyosgenized with bacteriophage that induces production of erythogenic toxin
|
|
|
3 characteristics of scarlet fever
|
strawberry tongue
diffuse erythmatous rash desquamation of skin 1 wk after onset |
|
|
the two post strept sequelae
|
acute rheumatic fever
acute glomerulonephritis autoimmune pathogensis |
|
|
s pyogenes, characteristics
gram ferment glucose to ___ catalase ___ sensitive to ____ |
gram negative cocci chains
facultative anaerobes glucose to lactose catalase neg sensitive to bacotracin |
|
|
SpyCEP does---
|
inactivates IL-8, soluble virulence factor of strep pyogenes
|
|
|
Describe the pathogensis of strep pyogenes
|
Encounter----Spread-----Damage
direct contact or inhale nuclei attach to mucosal epithelial cells by fibrils or M protein/ lipteichoic acid resist phag (capsule and M protein) invade tissue (enzymes) intense inflammatroy respones hemolysins and enzymes |
|
|
Lab DX for s pyogenes
|
plate specimen on SBA
apply bacitracin, look for inhibition remember! 5% resistant to bacitracin |
|
|
Tx for s pyogenes/strep pharyngitis
|
Penicillin G or V for 10 days
Macrolides (erythromycin) or cephalosporins |
|
|
Can early tx be counterproductive in strep pharyngitis?
|
yes, less time for develop antibodies and less tissue penetration with antiboitics
|
|
|
Diptheria is transmitted via
|
droplet nuclie
|
|
|
"bull neck" is seen in
|
Diptheria
|
|
|
sx for diptheria
|
sore throat, fever-- pallor, listlessness, tachycardia
|
|
|
Characteristics of C. diphteriae
|
club-shaped or Chinese letters
stain with methylene blue, beaded appearnce, garlic odor in culture |
|
|
c. diphteriae is stained with
|
methylene blue
|
|
|
"chinese letters"
|
corynebacterium diptheriae
|
|
|
exotoxin in c. diptheriae is due to
|
lysogenic beta phage with tox+ gene
|
|
|
MOA of toxin in C. diptheriae
|
B fragment binds to receptors, endocytosis
toxin cleaved by protease A fragment enters cytoplasm blocks protein synthesis by ADP ribosylating elongation factor 2` |
|
|
TX and prevention for diptheriae
|
passive immune with antitoxin
penicilin immune with toxoids |
