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52 Cards in this Set

  • Front
  • Back
Squamous cell carcinoma
Def
is centrally located and arise in segmental and subsegmental bronchi in response to carcinogens
Adenocarcinoma
Def
is most prevalent & presents more peripherally as masses or nodules & is prone to metastisis
Large Cell Ca:
fast-growing tumor that is peripheral
Bronchioalveolar Ca
arises from terminal bronchi & alveoli & is slower growing
Small Cell Ca:
arises as a proximal lesion in any part of tracheobronchial tree * most commonly seen in smokers
Stage of tumor refers to
size, location, whether lymph nodes are involved, and mets
Calculate Pack year hx
# packs per day x # of years smoked
Risk for Ca determined by
pack years, age of initiation, depth of inhilation and tar/nicotine levels in cigarettes.
Risk Factors for Bronchogenic Carcinoma: Environmental & Occupational Exposure
•Motor vehicle emissions
•Pollutants from refineries & manufacturing plants
•Incidence greater in urban areas as a result of pollutant buildup
•Radon: colorless, odorless gas found in soil & rocks; seeps into homes thru ground rock -high levels associated with lung Ca especially when combined with smoking
•Chronic exposure to industrial carcinogens: arsenic, asbestos, mustard gas, chromates, nickel, oil, & radiation
•OSHA laws to control exposure help decrease risk somewhat
Risk Factors for Bronchogenic Carcinoma: Genetics & Dietary Factors
•Familial predisposition
•Incidence in close relatives 2-3x that of general population regardless of smoking status
•Risk higher if diet low in fruits & veggies
•Carotenoids: Beta Carotene & Vitamin A may be important in reducing risk
•Vitamin E, Selenium, Vitamin C, Fat & Retinoids(Vit. A derivatives) may have preventive role
Clinical Manifestations of Bronchogenic Ca
•Insidious & asymptomatic until late in course
•Cough or change in chronic cough
•Wheezing -20% of pts.
•Dsypnea/stridor
•Dysphagia
•Weakness, anorexia, weight loss
•Fatigue
•Hemoptysis
•Fever
•Unresolved, repeated URIs
•Chest or shoulder pain-chest wall or pleural involvement
•CP, tightness, hoarseness
•Head & neck edema
•Pericardial or pleural effusion
Common Sites of Metastasis for Bronchogenic Ca
•Lymph Nodes
•Bone
•Brain
•ContralateralLung (opposite)
•Adrenal Glands
•Liver
Nursing Assessment of the Client with Lung Cancer
•General Data
Fever
neck and axillary lymphadenopathy
paraneoplastic syndromes(a disease or consequence as a result of cancer in the body e.g. CushingsSyndrome, Hypercalcemia, anemia)
Nursing Assessment of the Client with Lung Cancer
•Integumentary:
–Jaundice(liver mets); edema of neck and face(SVC syndrome), digital clubbin
Nursing Assessment of the Client with Lung Cancer
Respiratory:
–Wheezing, hoarseness, stridor, unilateral diaphragm paralysis, pleural effusions(late signs)
Nursing Assessment of the Client with Lung Cancer
•CV:
–Pericardial effusion, cardiac tamponade, dysrhthmias(late signs)
Nursing Assessment of the Client with Lung Cancer
•Neuro:
–Gait disturbances(brain mets)
Nursing Assessment of the Client with Lung Cancer
•Musculoskeletal:
–Pathologic fractures, muscle wasting
Interventions for Bronchiogenic Ca
Based on tumor size and mets
•Surgical resection-treatment of choice for early-stage non-small cell tumors without mets
Lobectomy:
single lobe removed
Bilobectomy:
two lobes of lung removed
Pneumonectomy:
removal of entire lung
Segmentectomy:
a segment of the lung is removed
Wedge Resection:
removal of a small, pie-shaped areas of the segment -not a curative resection
Chest wall resection
with removal of cancerous lung tissue for cancers that have invaded the chest
Closed-chest drainage (chest tube with underwater seal drainage): Indications and usage
–After all forms of chest surgery except pneumonectomy
–Promotes evacuation of air and fluid from the pleural space to permit full lung reexpansion
–Prevents mediastinal shift by equalizing pressures on both sides of the thorax
Closed-Chest Drainage
•Assessment:
–Amount & type of chest drainage
–Water-seal function (bubbling, suction pressure, amount of water in seal chamber)
–Adequacy of breath sounds & RR
–O2 saturation
Radiation Therapy
Indications
•Radiation therapy (RT)-useful for neoplasms that cannot be surgically resected but are responsive to RT
•RT may be used to reduce tumor size, make a tumor operable, or relieve pressure on organs
•May control spinal cord mets or superior vena caval compression
•Prophylactic brain RT to treat microscopic mets to brain
•RT relieves cough, CP, DOE, hemoptysis, bone & liver pain -weeks to months
Complications of RT:
esophagitis, pneumonitis, radiation lung fibrosis
Lung Ca Interventions :Chemotherapy
•Alters tumor growth patterns, treats distant mets, often an adjunct to surgery or radiation
Treatment-Related Complications: Chemotherapy
•Diminished cardiopulmonary function, fibrosis, pericarditis
•Pulmonary toxicity secondary to chemo
•Airway clearance is key-TCDB, Chest PT
•Assessment of gas exchange as tumor enlarges
•Decrease dyspnea with promotion of lung expansion
•Pulmonary rehab programs
•Relieving fatigue enhances
Causes of Laryngeal CA
•Tobacco
•Alcohol
•Exposure to asbestos, mustard gas, wood, leather, & metals
•Straining the voice
•Chronic laryngitis
•Riboflavin deficiency
•Family predisposition
Laryngeal CA
Risk Factors
•Occupational exposures: petroleum products, sawdust, asbestos, mustard gas, and other inhaled noxious fumes
•Chronic laryngitis and voice abuse
Laryngeal CA
Clinical Manifestation
•Hoarseness
•Pain
•Burning in throat when drinking or citrus juice
•Dysphagia
•Dyspnea
•Foul breath
•Weight loss
•Throat pain
•Neck mass
•Aspiration during swallowing
Tumor ablation
–removal while sparing undiseased tissue when possible
Total laryngectomy: for large glottictumors/fixation of the vocal cords
–When larynx removed, trachea is sutured to the neck and a permanent tracheostomyis created –therefore the ability to speak is lost and so is the sense of smell (air no longer enters the nose during breathing)
guidelines the need to remove secretions is evidenced by:
–coarse or “noisy” breath sounds
–↑ peak inspiratory pressures during volume controlled ventilation
–patients inability to generate cough
–visible secretions in the airway
–suspected aspiration
–↑ work of breathing
–deterioration of ABGs
–restlessness
–Feeling of secretions in chest (tactile fremitus)
–CXR shows atelectasisor consolidation
Larygeal CA
Potential Post-surgical Complications
•Airway obstruction
•Hemorrhage
•Carotid artery rupture
•Fistula formation
Postoperative Care
Laryngeal Ca
•Respiratory assessment, including trach tube care
•Maintain semi-Fowler’s or Fowler’s position
•Suctioning as needed
•CPT, ultrasonic nebulizers
•Oxygen therapy
•Adequate nutrition
•Wound drains/dressing care
Assess: ABC’s
•Status
•Physical
•Psychosocial
•Comfort
•Nutritional status
•Ability to swallow
•Respiratory status
–Function
–Airway patency
–Lung sounds
–Oxygen saturation
Clinical Manifestations of ARDS
•Restlessness
•Change in LOC
•Dyspnea –usually the earliest sign
•Tachypnea
•Accessory muscle use/retractions
•Flaring of nares(nostrils)
These signs typically appear 12-24 hours after initial injury to capillaries
Clinical Manifestations of ARDS
•Progressive deterioration of lung function
•Injury to alveolar epithelium and pulmonary microvasculature
•Arterial hypoxemia (PaO2 less than 50mHg) –resistant to O2therapy
•Decreased lung compliance and volumes
•NO indication of left ventricular failure
Alkalosis initially with low CO2levels (hypocapnia) and hypoxemia
•Decreased platelet count
•CXR shows consolidation about 24 hrs. after initial injury “ground glass” characteristics
PACO2
35-40
PAO2
80-100
HCO3
22-36
PH
7.35-7.45
•-Time cycled vent
terminates orcontrol inspiration after a preset time. Pure time cycling is rarley used for adults.(Newborns/Infants)
Pressure cycled vent
delivers a flow of air(inspiration) inil it reaches a preset pressure and cycles off, and expiration ocurs passivley. Inteded for short term use
Volume cycled vent
Most commonly used + presure vents today. Volume of air is regulated, Volume of air to be delievered with each inspirtion is preset.
Complications Related to Mechanical Ventilation
•Hypotension& Fluid retention
•Barotrauma& ARDS
•Stress Ulcers & Malnutrition
•Infection
•Ventilator dependence
Criterial for a
vent weaning trial
•Respiratory Criteria
•-RR < 38 breaths/min
•-Tidal Volume > 325ml
•-FiO2 < 50
Criteria for a Weaning Trial
•Other Criteria to consider:
•-Improvement, correction of active disease process
•-Nutritional & fluid status
•-Stable cardiac, renal & cerebral status
•-Afebrile
Consider rentubating if
RR>30
Increased PaC02
abnormal breathing pattern
dysrythmias
diaphoresis
anxiety
dyspnea
Nursing careArtificial Airway
Secure tube -placement mustbe verified –how?
•**Check for end-tidal CO2**
•Check for bilateral breathe sounds
•Check symmetry of chest expansion
•Chest X-ray must be done
Also check for air emerging from the ET tube
•Ensure humidification
•Check cuff for proper inflation pressure
•Elevate HOB to ease respiratory effort
•Sedation sometimes needed:
•*pancuronium(Pavulon) *vecuronium(Norcuron)
•*succinylcholine(Anectine) –paralyzing agents