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19 Cards in this Set

  • Front
  • Back

which muscles are not paralysed during REM

Eye muscles


Diaphragm

which kind of respiratory control is used during sleep

only reflex/ autonomic


(no cortical control)

what controls the voluntary breathing:

Voluntary breathing (when awake) comes from the motor homunculus (located in the brain between motor areas for the shoulder and the trunk).

what is the Pre-Botzinger Complex

The cluster of respiratory nuclei. Neurones reciprocally inhibit each other (when one fires, the other stops) which allows breathing.

breathing awake vs asleep

10% reduction (6.28 to 5.44 l/min)


lower tidal volume (500 ml vs 350)


lower O2 sat


lower frequency

O2 changes during sleep

O2 sat decrease but not too much because the oxygen dissociation curve is sigmoid

CO2 changes during sleep

CO2 levels rise (Hypercapnia)


o CO2 level required to trigger breathing is lower when awake than when we are asleep (0.5 kPa)




Reduced sensitivity of chemoreceptors to CO2 during sleep



what is hypercapnia and hypocapnia

increased/ reduced CO2 blood levels

what is the apnoeic threshold

the threshold overwhich CO2 level has to be in order to allow us to breathe

what is central sleep apnea?

the CO2 levels do not raise above the apnoeic threshold and so breathing stops




faulty CO2 chemoreceptors

what is obstructive sleep apnoea

occlusion of the phalangeal airway during sleep




the person try to breathe but cannot

heart failure and sleep apnoea

heart failure is associated with central sleep apnoea because patients hyperventilate so have a low PaCO2

effects of the motor cortex on cough

inhibitory.

efferent pathways for cough

motor cortex: inhibitory


cough centre in the medulla: stimulatory

problems of heart failure and lungs

can cause pulmonary eodema

problems of pulmonary oedema

activation of J receptors


increase ventilation


low CO2


when they go to sleep theu do not breathe (do to imbalance on the chemical components)


stain stoke respiration

what is chain and stokes respiration

which drugs make asthma worse

beta blockers


non-steroid anti-inflammatory (eg ibuprofen)

asthma symptoms

wheezing


cought


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