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19 Cards in this Set

  • Front
  • Back
A-a gradient
Alverolar (A) - arterial (a) gradient

normal gradient is 10-15 mmHg

above 15 is abnormal - denotes a lung disease (as opposed to neurological problem, chest wall abnormality etc)
alveolar gas equation
760 is atmospheric pressure

760 - 47 = 713 (subtracted water vapor)

713 x .21 = 150 (21% O2 in the air)

alverolar gas equation = 150 - CO2/0.8
normal pH range
7.35-7.45
normal pO2
75-100mmHg
normal pCO2
35-40mmHg
HCO3 normal
22-30 mmol/l
O2 sat normal
95-100%
a hypoxic patient with increased pCO2 and a normal A-a gradient
hypoventalation
a hypoxic patient with increased pCO2 and abnormal A-a gradient
COPD, obstructive sleep apnea,

some sort of lung disease
hypoxic patient with normal/low pCO2 and normal A-a gradient
high altitude
a hypoxic patient with normal/low pCO2 and increased A-a gradient
V/Q mismatch or shunt
telling the difference between V/Q mismatch and shunt
V/Q mismatch patients will respond to 100% O2
T/F its possible to have 2 respiratory and metabolic disorder can happen at the same time (alkalosis or acidosis)
False - can never happen

2 metabolic and 1 respiratory can occur
double acid-base disorders
1 metabolic, 1 respiratory

2 metabolic process

can't have respiratory alkalosis + respiratory acidosis
important causes of respiratory alkalosis
sepsis, fever, pregnancy, thyrotoxicosis
important causes of respiratory acidosis
atelectasis, pneumonia, pneuothorax, pulm edema, obstruction, PE

chest wall pain, neuromuscular problems, CNS supression

anything that causes hypoventilation
important causes of metabolic acidosis
if increased anion gap -MUDPILES

Methanol
Uremia
Diabetic Ketoacidosis
Paraaldehyde
Isoniazid
Lactic acidosis
ethylene glycol
Salicylate


normal anion gap

diarrhea
fistula
ileal loop
renal tubule acidosis
carbonic anhydrase inhibitor (acetezolamide)
kussmaul respiration
deep labored breathing seen with metabolic acidosis
important causes of metabolic alkalosis
vomiting

hypochloremia

excess diuretics

high levels of aldosterone