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12 Cards in this Set
- Front
- Back
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What therapeutic goals are accomplished with reproductive drugs?
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enhance/manipulate cycling and pregnancy
prevent cycling/pregnancy terminate pregnancy treat infertility |
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How do the reproductive drugs work?
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analogs (or identical to) endogenous hormones associated with the reproductive cycle
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What are the exogenous GnRH analogs?
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Gonadorelin
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What are the prolactin enhancers?
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metoclopramide
domperidone *dopamine antagonists, which increase PRL secretion |
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What are the PGF 2alpha analogs?
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dinoprost
cloprostenol |
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What are the estrogens available?
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estradiol
DES (must be compounded) *DO NOT USE DES in FA! |
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What are the available progestins?
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altrenogest
melengestrol acetate progesterone (CIDRs) megestrol (feed additive) |
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What are the available androgens?
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testosterone (implants, injection)
stanozolol (controlled, abuse in humans) boldenone trenbolone (implants) nandrolone *Schedule III drugs b/c anabolic steroid abuse in people |
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What is finasteride?
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"anti-androgen"
-inhibits conversion of testosterone (inactive) to 5-alpha-DHT (active) *used in dogs for prostatic hypertrophy |
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What is the function of LH?
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female: formation of CL
male: androgen production |
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What is the function of FSH?
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female: development and maturation of follicles
male: spermatogenesis |
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How is the estrus cycle regulated?
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GnRH is released from the hypothalamus
GnRH stimulates pituitary to release LH, FSH LH, FSH bind targets in repro tract estrodiol, progesterone produced *progesterone has negative feedback on pituitary and hypothalamus *inhibin released from follicles has negative feedback on the pituitary |
