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56 Cards in this Set

  • Front
  • Back
suspensory ligament of ovary
ovarian vessels
cardinal ligament
uterine vessels (inferior)
round ligament
no important structures, but attaches to the labia minora (gubernaculum)
broad ligament
basically contains all the structures , broadly runs from ovary to uterine tube to uterus
where does the acrosome come from

the tail?
acrosome --> golgi

tail --> centriole
what is the energy supply of sperm?
fructose (has highest metabolic rate in cells)
what is the FSH/LH ratio in childhood

adulthood and puberty?
FSH>LH


LH>FSH
why can't leydig cells make mineralocorticoid or cortisol?
They don't have 21 or 11 hydroxylase... basically they can go over but not down in the synthesis pathway.
what happens to testosterone in adipose tissue?
gets converted to estrogen via aromatase
What does DHT do?
the things that make you male on the outside plus prostatic growth
what does T do?
the things that make you male on the inside plus penile and testis growth
what is abrupto placentae associated with that is really bad?
DIC
how does HPV predispose to cervical carcinoma?
E6 and E7 block p53 and Rb respectively
severe menstrual pain, infertility
endometriosis
endometriosis within myuometrium
adenomyosis
most common causes of endometritis
staph and strep

granulomatous endometritis is caused by TB
post menstrual vaginal bleeding
endometrial hyperplasia and endometrial carcinoma
what is the most prognostic factor for endometrial carcinoma, the most common gynecologic malignancy?
endometrial CA
benign, estrogen sensitive tumor more common in blacks, commonly presents with menorrhagia
leiomyoma
vaginal adenosis
precursor to vaginal clear cell carcinoma
sarcoma botryoidies
happens in kids<5
Desmin +
Rhabdomyosarcoma looks like a bunch of grapes protruding into the vagina
Features of PCOS

Hormones
Findings
Increased LH and testosterone, decreased FSH

Amenorrhea, infertility, obesity, hirsutism.

Multiple small follicular cysts, stromal fibrosis.

(insulin resistance causes increased ovarian androgens causes increased LH and then a worsening of the cycle)
which cyst causes menstrual irregularity?
corpus luteum cyst

hemorrhage into persistent corpus luteum
which cyst is associated with choriocarcinoma and moles?
theca-lutein cyst
which cyst is associated with hyperestrinism and endometrial hyperplasia?
follicular cyst
which ovarian germ cell tumors make hCG?
dysgerminoma, chioriocarcinoma
which ovarian germ cell tumors make AFP
endodermal sinus tumor (aggressive)

ovary or sacrococcygeal area
What is the most common germ cell tumor of the ovary?
Mature teratoma makes up 90% of germ cell tumors.

Immature teratoma is much less common and is aggressive
what is the monodermal teratoma affecting females?
struma ovarii
pseudomyxoma peritonei
associated with mucinous cystadenocarcinoma of ovary or an appendiceal tumor

accumulation of mucinous material in peritoneal cavity
Brenner tumor
benign tumor resembles bladder epithelium interspersed with fibrous stroma
Meig's syndrome
triad of ovarian fibroma, ascites, hydrothorax
fibroma?
bundles of spindle shaped fibroblasts
what is associated with call-exner bodies and hyperestrinism?
granulosa cell tumor
mets to the ovary: most common sources.
GI, breast, endometrium
woman presents with labial nodule
papillary hydradenoma: benign apocrine tumor
clue cells
gardnerella vaginitis
most common cause of breast mass in postmenopausal woman?
carcinoma
most common breast tumor <25 years
fibroadenoma

may become painful with pregnancy
most common breast lump 25-menopause
fibrocystic disease

diffuse pain, multiple lesions, often bilateral
what drugs cause bitch tits?
spironolactone
digoxin
cimetidine
alcohol
ketoconazole
marijuana
which is more common for prostatitis:

bacterial or abacterial
abacterial
BPH: what lobes
lateral and middle (periurethral)
Prostate cancer: what lobes

what assays
posterior lobe (peripheral zone)

PAP
PSA (decreased free PSA)
Alk phos

Gleason grading system
increased risk of carcinoma with cryptorchidism: what types?
seminoma and embryonal carcinoma
most testicular tumors are ______ tumors
germ cell tumors
painless testis enlargement, can get increased hCG
seminoma

very radiosensitive
painful, hCG often increased; second most common germ cell tumor
embryonal carcinoma
malignant tumor that always has increased hCG
choriocarcinoma
tumor with increased AFP
endodermal sinus tumor
Non germ cell tumors
Leydig cell - Reinke crystals, benign, secretes androgens (bitch tits in men, precocious puberty in boys)

Sertoli cell - benign, no endocrine symptoms

Testicular lymphoma - most common testicular cancer in older men
which testicular tumor can have fried egg appearance?
seminoma
weird cause of priapism (thrombosis)
venous thrombosis of corpora carvernosa
flutamide
nonsteroidal competitive inhibitor of androgens at T receptor
terbutaline/rotodrine
Beta-2 agonists, relax uterus
anastrazole
aromatase inhibitor