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21 Cards in this Set

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What is responsible for external gential differentiation? Internal?
External- DHT
Internal- Anti Mullerian Hormone
Inguinal Hernia
Incomplete closing of the inguinal canal allows viscera to slip through.
Scrotal Muscle Action during cold
Contraction of Cremaster and Tunica Dartos muscles.
Testosterone Effects before birth
1.)Testicular descent
2.) Masculinizes Reproductive tract and Genitals
Testosterone effects on reproduction
1.) Growth and maturation of reproductive system at puberty
2.) Essential for Spermatogenesis
3.) Maintains reproductive tract through adulthood.
4.) Sex drive at puberty
5.) Controls GnRH
Testosterone effects secondary sexual characteristics
1.) Induces pattern of hair or feather growth
2.) Thickens vocal cords
3.) Muscle growth
4.) Bone Growth at puberty then closure of epiphyseal plates
5.) Aggressive behavior
Hormonal Control of Spermatogenesis
1.) Testosterone induces mitotic and meiotic division
2.) FSH induces remodeling of spermatids into motile spermatozoa
Negative Feedback of Testosterone
1.) Inhibits GnRH in Hypothalamus
2.) Decreases reponse of AP LH cells to GnRH
Negative Feedback of Inhibin
1.) Acts Directly on AP to inhibit FSH
Effects of LH Surge
1.) Prostaglandins to rupture follicle wall
2.) Differentiates follicular cells to luteal cells.
Tonic LH Effects
Promotes follicular development
LH

Stimulus?
Estrogen on GnRH and LH secreting cells in AP.

Inhibition?
Progesterone on GnRH
and low Estrogen.
Role of Progesterone in endometrium
Vascularizes endometrium and stocks it with Glycogen.
3 goals of uterine contraction at partuition
1.) Dilation of cervix
2.) Birth
3.) Delivery of placenta
Why would an XX human develop testes?
They have an extra 40kb of DNA which contains the SRY gene.
What do Wolffian Ducts become?
Seminiferous tubules, epididymus, vas deferens
DHT is responsible for what during differentiation.
Development of scrotum and penis.
Secondary sex characteristics.
Estradiol in the fetal brain controls what?
Masculinization of hypothalamus by determining tonic/phasic control of LH.
SF-1
Orphan Transcription Factors
What happens to the sensitivity of the hypothalamus to estrogen and testosterone during puberty
Sensitivity to negative feedback decreases and more GnRH is released.
What is Clearance?
How much of a substance is excreted by the kidneys.