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53 Cards in this Set

  • Front
  • Back
Distentin of unruptured graafian follicle. may be associated with hyperestrinism and endometrial hyperplasia
Follicular Cyst
Corpus luteum cyst
Hemorrhage into persistent corpus luteum.
regresses spontaneously
Theca-Lutein Cyst
often bilateral and multiple
due to gonadotropin stimulation
Associated with Choriocarcinoma and moles
chocolate cyst
Blood containing cyst from ovarian endometriosos
Dysgerminoma
Malignant (equivilant to male seminoma)
*Sheets of uniform cells*
** look for hCG, LDH markers**
Choriocarcinoma
Rare but malignant
*large hyperchromatic syncytiotrophoblastic cells
Yolk Sac (endodermal sinus) tumor
Aggressive malignancy of ovaries
*looks like yellow friable mass*
*** look for high levels of AFP***
Mature teratoma
Dermoid cyst
**most frequent benign ovarian tumor**
immature teratoma
aggressively malignant
struma ovarrii
contains functional thyroid tissue
*presents as hyperthyroidism*
Abruptio placenta
Painful bleeding in 3rd trimester
Abrupt detachment/death
*assiociated with DIC, increased risk with smoking, HTN, cocaine*
Placenta accreta
decidual layer allows placenta to attach to myometrium. **no seperation of placenta after birth**

***massive bleeding after delivery***
Ectopic pregnancy
most often in fallopian tube,
placenta previa
attachment of placenta to lower uterine segment
*painless bleeding in any trimester*
Dysplasia and carcinoma in situ
begins at basal layer of squamo-columnar junction
*associated with HPV 16,18 can progress slowly to invasive carcinoma if not treated*
Invasive carcinoma
Squamous cell carcinoma
look for koilocytes
Endometriosis
Non - neoplastic
abnormal locations outside uterus
**cyclic bleeding **
Adenomyosis
Endometrium within the myometrium
Endometrial hyperplasia
endometrial gland proliferation from excess estrogen.
*manifests as postmenopausal vaginal bleeding.
Endometrial carcinoma
MOST COMMON GYNECOLOGIC MALIGNANCY
*55-65 years present with vaginal bleeding*

**prolonged use of estrogens without progestins**
Liomyomata
MOST COMMON OF ALL TUMOR
Just fibroids
*does not progress to leiomyosarcoma*
Leiomyosarcoma
Bulky irreg shaped tumor with central necrosis and hemorrhage
*may protrude from cervix and bleed, most common seed in middle aged women*
Serous cystadenoma
Bilateral ovarian tumor with fallopian tube like epithelium
*CA-125 is general ovarian cancer marker*
Serous Cystadenocarcinoma
Ovarian tumor, malignat and frequently bilateral
**risk factors BRCA-1, HNPCC**
Mucinous cystadenoma
Multilocular cyst lined by mucus secreting epithelium,
*benign*
Mucinous cystadenocarcinoma
Malignant, pseudomyxoma peritonei
*intraperitoneal accumulation of mucinous material from ovarian tumor*
Brenner Tumor
Benign Looks like Bladder
Meigs syndrome
Triad of
Ovarian fibroma
Ascites
and hydrothorax
*pulling sensation in groin*
Granulosa cell tumor
Secretes Estrogen - precocious puberty in kids
Krukenberg tumor
GI malignancy that metastasizes to ovaries causing a mucin secreting signet cell adenocarcinoma
Clear cell carcinoma
affects women exposed to DES in utero
Squamous cell carcinoma of the vagina
2nd to cervical SCC
Sarcoma botryoides
Rhabdomyosarcoma variant (vaginal)
affects girls<4
Spindle shaped tumor cells that are desmin postive
Bartholins gland cyst
Rare
Pain in labia majora
can result from previous infection
Small mobile firm mass with sharp edge in the breast
MOST COMMON TUMOR IN <25
**increase size and tenderness with increase estrogen**
Fibroadenoma
Intraductal papilloma (breast)
Small tumor that grows in lactiferous ducts beneath areola
**serous or bloody nipple discharge**
Phyllodes tumor (breast)
Large bulky mass of connective tissue and cystes "leaf like"
most common in 60's
What are the genes for malignant tumors
erb-B2
HER-2
EGF
Ductal Carcinoma in situ (breast)
*Fills ductal lumen*
early malignancy without basement membrane penetration
Invasive Ductal (Breast)
Firm Rock hard mass
**worst and most invasive**
****MOST COMMON BREAST CANCER****
invasive lobular (breast)
Orderly row of cells
often multiple
bilateral
Fleshy cellular, lymphatic infiltrate tumor
Good prognosis
Medullary (breast)
Comedocarcinoma (breast)
Ductal, CASEOUS necrosis
*subtype of DCIS*
Inflammatory (Breast)
Dermal lymphatic invasion by breast carcinoma
Peau d'orange
Pagets disease (breast)
Eczematous patches on nipple
** suggest underlying carcinoma**
Acute mastitis
breast abcess during breast feeding
*s. aureus*
Fat necrosis (Breast)
result of injury to breast tissue (abuse)
What is the nemonic for gynecomastia
"some drugs cause awesome knockers"
**Spironolactone, digitalis, Cimetidine, Alcohol, Ketoconazole**
What is the innervation for Male emission of sperm
Sympathetic
Hypogastric nerve
What is the innervation for the male ejaculation
Visceral and SOMATIC nerves
Pudenda nerve
What Do sertoli cells secret
Inhibin which inhibits FSH
also secret androgen binding protein (ABP) to maintain levels of testosterone

***produce anti mullerian hormone***
What do Leydig Cells do
Secrete Testosterone
What does the prostate contribute to the ejaculate
***ZINC***
and fibrinolysin to activate the sperms