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64 Cards in this Set

  • Front
  • Back

When is a bitch considered to have a delayed puberty?

2 years

How can you demonstrate ovulation has occured in the last 60 days?

measure serum progesterone concentrations >2.0 ng/mL

What maybe an underlying cause of delayed puberty?

chromosomal abnormality or


abnormal complement of sex chromosomes

An increased interestrus interval is also called

prolonged anestrus

What brred of dog only cycles once per year?

Basenji

What is the most common reason for prolonged anestrus

failure to observe signs of estrus

What RX may contribute to prolonged anestrus?

glucocortiboids


anabolic steriods


androgens


progesterone

What disease can cause prolonged anestrus?

hypothyroidism

MOA of how hypothyroidism causes prolonged anestrus

unknown, but possibly due to something affecting thyrotropin-releasing hormone which also affects prolactin and thyroid function

How long after supplementing thyriod will bitches return to cycling

6 months

____ hormone producing ovarian cysts have been noted to cause a prolonged interestrus intervals

progesterone producing

How are progesterone producing ovarian cysts TX?

SX

What is silent estrus

Normal cyclical activity without obvious external signs of proestrus or estrus

What criteria must be used to induce estrus

2.5 years old


no underlying PE abnormalitiy

What RX can be used to induce estrus?

prolactin inhibitors (cabergoline/bromocriptine)


equine chroionic gonadotropin (eCG)


human chorionic gonadotropin (hCG)


gonadotropin releasing hormone (GnRH)


Estrongens

Why can you not induce estrus by shortening the luteal phase using prostaglandins?

The luteal phase is followed by a prolonged period of anestrus

What RX is the best to to cause estrus induction

administration of prolactin inhibitors


- prolactin inhibitors

What is a split estrus?


When is it most commonly seen?

a short interval betwwen clinical signs of estrus


most frequently seen at the pubertal estrus

What can be a cause of prolonged proestrus or estrus? What can be other effects?

estrogen secreting follicular cyst


bone marrow suppression - anemia/thrombocytopenia

Although ovarian neoplasms do not metastasize, why should care be taken during OHE?

if reptures the growth can lead to seeding

How do you prevent recurrance of vaginal hyperplasia/vaginal prolapse?

OHE

What is the most common reason for fialure of conception

inappropriate timing of mating

What is a reliable and accurate method to determine the optimum time to mate?

LH levels - but difficult in practice


Progesterone - 4-6 dyas after >2.0 ng/dL


List the infectious causes of pregancy loss (6)

canine herpes virus


brucella canis


canine adenovirus


canine parvovirus


canine distemper virus


Toxoplasma gondii


During early pregnancy, this results in fetal death and mummification

canine herpes

Abortion and infertility generally occur between the 45-55 day of pregnancy

brucella canis

This can cause birth of dead or weak pups or those that die within a few days after parturition

canine adenovirus

What diseases should be ruled out for vaginitis?

UTI


lymphoid follicle hyperplasia


dermatolical leions

What age does juvenile vaginitis occur?

pre-pubertal bitches

MC clinical sign of juvenile vaginitis?

purulent vulvar dischage

TX for juvenile vaginitis and problems with TX?

may respond to AB, but return when TX is discontinued

How can the condition (puppy vaginitis) naturally resolve

after the first estuous cycle


neutering should be delayed until first estus

What is a persistent hymen?

occurs at the junction of the vagina and vestibule where the paramesonephric duct joins the urogenital sinus.

What are C/S of bithces with a persistent hymen?


DX?

breeding diffulties


chronic vagnitis


urinary incontience


manual palpation


What is an inverted vulva?

prepubertal bitches


vulva is inverted to the pont that it is hidden from view

What are possible complicates to an inverted vulva?

vulvular discharge


UTI


let them have the first heat


if alreaded OHed, then episioplasty

Wht is vaginal hperplasia


aka


vaginal prolapse

under estrogen


edematous ventral fold in the distal vaginal mucosa immedately cranial to the urethral opening


=EDEMA

What will happen if a bitch has vgainal hyperplasia during subsequent estrus cycles?

recur

If a bitch is bleeding after breeding, what should be expected?


TX?

vaginal tears


AB

What is the behavior of vaginal and vulvar neoplasia

80% benign

MC benign and malignat vaginal tumors

leiomyoma


leiomyosarcoma

Primary abnormalites of sperm are described as?


Where do they occur?

all head defects


prximall coiled tails


proximal hytoplasmic droplets



occurs in the testis during spermatogenesis


Secondary sperm abnormalities include?


Where do they occur?

detached heads


bent tails


distal cytoplasmic droplets



occur during epididymal transport

What are infectious causes of orchitis and epididymus

Brucella sp


Escherichia coli


mycoplasma


Dogs with ideopathic oligospermia (low sperm count) can be treated with this medication

gonadotrpin-releasing hormone +/- human chorionic gonadotropin

What other conditions are dogs with benign prostaticd hypertrophy predsiposed to?

prostatic cysts


infections


prostatic infections


Pathogenesis of BPH?

unknown


Dihydrotesterone, testosterone, estradiol and some growth factors are involved in prostatic growth

CS of BPH:

constipation


drippin of sanguineous discharge from penis


bloodly urine/semen


difficulty urinating

DX of BPH

symmetrically enlarged and firm


no pain


on rads postatomeglay suggeste >70% the difference between the sacral promonatory and the pubis

TX for BPH

neuter


finasteride - causes programmged cell death or apoptosis

This is common in sexually intact dogs and can be acute or chronic

prostatitis

CS of acute prostatitis

fever


pain


depression


straining to urinate/deficate


stiff legged gait


hematuria


edema of scrotum


pollakiuria

TX of prostatitis

SX:


marsupialization


penrose drain placement


partial prostectomy


MEDICAL TX:


AB


fenasteride TX


(better response with AB and fenasteride)

At what age should the testes be descended by

6 months

How is cryptorchidim inherited

autosomal recessive and both males adn females carry it and pass it to offspring

Why would a crypt orchidism stil have animals with sexual desire and able to breed?

it dosen't affect testosterone production

How can bilateral cryptorchidism be diagnosed hormonally?

basteline testosterone <0.02 ng/Ml = no testicle


testosterone 0.1-1.2 ng/mL = abdominally retained


1-5 ng/mL = two descended testicles

What testicular tumor is more evident in retained testicles/

Sertoli cell

What are the 3 most common testicular tumor types

Sertoli cell


seminomas


interstitial cells

Why is castration the TX of choice for testicular tumors

high incidence of bilateral neoplasia

This testicular tumor has a feminizing paraneoplastic syndrome caused by estrogen secretion and secondary estrogen induced pancytopenia

sertoli cell tumors

What are clinical signs of paraneoplastic syndrome of sertoli cells?

bilaterally symmetric alopecia of the trunk/flanks with hyperpigmentation


dry easily epilated coat


gynecomastia


penduluous preputial sheath


attaction of male dogs


bone marrow hypoplasia with non-reg anemia

These are tumors of the spermatogenic cells

seminomas

These testicular tumor are an incidental finding at necropsy

interstitial (Leydig) cell tumors