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11 Cards in this Set

  • Front
  • Back
causes of irregular uterine bleeding
adenomyosis
endometrial polyps
(endocervical polyps)
chronic endometritis
abnormal proliferation
-anov, menarche/meno, stress, OCP, obes, thin
endometrial adenocarcinoma
endometrial carcinoma
leiyomyo & leiyomyosarcoma

(functional stroma tumors: thecoma, granulosa cell tumor, sertoli/leydig)
glands on glands
hemosiderin MPs
pelvic pain, dysmen, abnrml bleeding
adenomyosis
glands on glands
hemosiderin MPs
pelvic pain, kidney
endometriosis
over 40 years
irregular vaginal bleeding
endo polyps
menarche
chronic endometritis
irregular bleeding
plasma cells in endometrial stroma
endometritis
bugs assocd w/endometritis
Neisseria, chlamyd, mycoplasmas
hyperplasia most likely to progress to cancer
complex hyperplasia with atypia

(29% progressed- comp to 1% with just hyperplasia)
two presentations of endomtrial carcinoma
Well differentiated
-no p53 mutation, pos est & progest R's
-59 y/o (rare under 40)
-hysterectomy curative

Poorly differentiated
-69 y/o
-p53 mutation, R negative
-aggressive
endometrial carcinoma mets to...
Early: pari aortic & iliac lymph nodes

Late: lung & liver
(poorly differentiated)
leiomyosarcoma mets to...
lung
tumors of endometrial stroma
stromal nodule
low grade stromal sarcoma
-high survival rate (90%)
-slow growing
-frequently recur
high grade stromal sarcoma
-poor survival (20%)
-mets to lung & abdo