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15 Cards in this Set

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Where d omost ectopic pregnancies implant?
Fallopian tubes
What are the risk factors for ectopic pregnancy?
Prior ectopic pregnancy
Hx of PID, tubal ligation, tubal reversal or other tubal sx,
Mullerian anomalies,

P4 IUD, Assisted reproduction, DES exposure, Cigs
Whats the normal progression of pregnancy?
Fertilization in fallopian tubes --> in utero in-planting by day 5 --> BHCG doubles every 2 days up to 10 weeks --> P4 inc. by >20 --> 5 weeks = transvaginal US shows sac --> 6 weeks = yolk sac and fetal pole 7 weeks = fetal cardiac activity
By what week do we see fetal cardiac activity?
week 7
Pt comes in with pain, bleeding, + preggo test, tubal rupture 6-8 weeks, cornual rupture 10 weeks. Dx?
Tubal ectopic pregnancy
What are the symptoms of a ruptured ectopic pregnancy
tender abdomen, distended abdomen, rebound tenderness, guarding, tachy, unclotted blood in culdocentesis, low Hb

US = intrabdominal fluid, empty uterus or pseudosac
T/F: until cardiac activity is seen in utero, assume ectopic pregnancy
TRUE
How do we manage an ectopic pregnancy?
Methotrexate
Linear Salpingostomy = hole in tube
Salpingectomy = removal of tube
Laparotomy = do if theres lots of blood loss
Laparoscopy
What ectopic pts are the perfect candidates for methotraxate?
They need to be RELIABLE, stable, healthy, compliant

US shows no intrauterine pregnancy
D+C shows no chorionic villi
No fetal cardiac activity
Normal LFTs, renal function tests, CBC
Pt presents with signs + symtoms of ectopic pregnancy = Pt comes in with pain, bleeding, + preggo test, tubal rupture 6-8 weeks, cornual rupture 10 weeks. = it hasn't ruptured. What do you do after giving her Methotrexate?
test for Rh status and give her Rhogam if Rh negative
Whats our methotrexate follow up in the pt from previous question?
Day 1 = baseline labs
Day 4 - HCG
Day 7 = HCG, CBC, renal panel, LFTs
Give dose 2 of methotrexate and repeat if a 15% drop in HCG has not occured

Follow weekly HCG levels until negative
Whats the Sx route of Ectopic pregnancy management?
Pt is hemodynamically unstable = bleeding a lot = Laparotomy

Pt is Stable = Laparoscopy
Salpingectomy (=take out whole tube) is used for ectopic pregnancy in what instances?
second ectopic, same tube
Childbearing complete
Uncontrolled bleeding
Severe tube damage
Salpingostomy (=incision into tube, dissect pregnancy) has what outcomes?
70% intrauterine pregnancy
84% subsequent tubal patency
12% subsequent ectopic pregnancy
15% persistent trophoblastic disease

Follow HCG to Zero
PT has ectopic pregnancy. What can you tell her about her subsequent risk of another ectopic pregnancy?
After 1 risk is 12%

10 fold inc. after 2