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13 Cards in this Set
- Front
- Back
embryonic derivation of ovarian stromal cells
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retroperitoneal mesenchyme
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ovarian stroma cells include the following types...
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granulosa (surround oocyte)
theca (surround granulosa) |
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embryonic derivation of ovarian germ cells
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allantois?
migrate thru yolk sac to retroperitoneal mesenchyme |
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mimic appendicitis
at risk for ovarian torsion |
follicle cyst
includes BOTH granulosa & theca |
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sclerocystic ovarian change found in...
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POCS
Stein-Leventhal Syndrome |
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Mullerian cell types
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serous (fallopian tube)
endometrial endocervical (mucus) |
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source of epithelial ovarian tumors
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epithelial inclusion cyst
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types of epithelial ovarian neoplasms
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serous
-cystadenoma (benign) -serous carcinoma -borderline serous (transition between the two) Mucinous -pseudomyxoma peritonei -mets from appendix/colon Endometrioid tumors -often coexist w/uterine Clear Cell Carcinoma Transitional Cell Tumors (Brenner): benign, bladder epi |
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sex cords give rise to...
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sertoli & leydig
granulosa & theca (from mesenchyme) |
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non-functional ovarian stromal tumors
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ovarian fibroma (middle age, rare under 30, no steroid production)
-Meig's syndrome: ascites & pleural effustion fibroma-thecoma (stroma + thecal cell) |
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functional ovarian stromal tumors
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Granulosa cell tumors
-estrinemia, usually benign -abnormal bleeding, endometrial hyperplasia, carcinoma -post menopausal Thecoma -lipid laden stromal or thecal cells -estrinemia, unilateral -abnormal bleeding, hyperplasia, carcinoma -Meig's syndrome Sertoli-Leydig cell tomors (rare in ovary) -androgenic in 30% of cases -young women (avg 25 yrs) |
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Germ Cell Tumor types
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Teratomas
-mature cystic: benign, "dermoid cysts", teeth -malignant transformation: rare, squamous cell carcinoma -immature: young women, malignant, mets via implantation & lymph -Monodermal: 1 tissue type, struma ovarii & ovarian carcinoid Dysgerminoma: -like seminoma -malignant, respond well to radiation -most common malig ovarian tumor Endodermal Sinus Tumor (yolk sac tumor): -AFP & alpha antitrypsin -rare -younger than 30 Choriocarcinoma: - beta hCG -gestational or non-gestational -malignant trophoblasts |
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eosinophilic globule in cell cytoplasm
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alpha fetoprotein
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