Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
24 Cards in this Set
- Front
- Back
|
FSH
|
stimulates growth of follicles (FSH receptors on granulosa cells --> stimulates primary follicles --> stimulates aromatiziing enzymes to make estradiol --> estradiol increases FSH receptors --> oocyte grows and completes M1)
|
|
|
LH
|
induces ovulation 36 hrs after release/24 hrs after peak (continuation of meiosis, luteinization of granulosa cells, prostaglandin synthesis for digestion of follicular wall); stimulates steroid synthesis in ovary (C-27 cholesterol to C19 androgen, androstenedione)
|
|
|
Estradiol (E2)
|
negative feedback to pituitary to suppress FSH release (low levels); stimulates release of LH (high levels); puberty (menarche, anovulatory cycles, corpus luteum devo); fertile life (prolif of endometrium, withdrawal bleed), pregnancy (sustained uterine growth, mammary gland devo), menopause (preceded by anovulatory cycles, vasomotor flashes), post menopause (maintenance of female sex organs, bone loss)
|
|
|
Estrone (E1)
|
other forms of estrogen (see estrogen fxns)
|
|
|
Estriol (E3)
|
other forms of estrogen (see estrogen fxns)
|
|
|
Progesterone
|
prepares endometrium for implantation (luteal), prevents maternal immune rejection of trophoblast (inhibits production of cytolytic cytokines), smooth muscle relaxant (constipation, GI reflux), uterine quiescence (prevents oxytocin receptors + gap junction formation until onset of labor), inhibits ovulation
|
|
|
GnRH
|
pulsative; causes pulsatile release of LH/FSH from pituitary
|
|
|
hCG
|
maintains corpus luteum; finds to LH/CG rectpro to activate adenylyl cyclase and leads to steroidogenesis, binds to TSH receptors
|
|
|
Anti-Mullerian Hormone
|
causes paramesonephric ducts to degenerate, causes a continuous duct system, makes Leydig cells make testosterone
|
|
|
Prostaglandins
|
mediator of labor; E/F, receptors in decidua/myometrium
|
|
|
Oxytocin
|
mediator of labor; potent uterine stimulant, receptors in myometrium, fetal membranes (amnion), decidua
|
|
|
Other labor mediators
|
progesterone (decrease allows increased levels of PGF2 alpha; reduced uterine levels may preceed labor), estrogen (myometrial hypertrophy, upregulates gap junctions + oxytocin receptors), cortisol (from fetus, may trigger labor)
|
|
|
FSH
|
stimulates growth of follicles (FSH receptors on granulosa cells --> stimulates primary follicles --> stimulates aromatiziing enzymes to make estradiol --> estradiol increases FSH receptors --> oocyte grows and completes M1)
|
|
|
LH
|
induces ovulation 36 hrs after release/24 hrs after peak (continuation of meiosis, luteinization of granulosa cells, prostaglandin synthesis for digestion of follicular wall); stimulates steroid synthesis in ovary (C-27 cholesterol to C19 androgen, androstenedione)
|
|
|
Estradiol (E2)
|
negative feedback to pituitary to suppress FSH release (low levels); stimulates release of LH (high levels); puberty (menarche, anovulatory cycles, corpus luteum devo); fertile life (prolif of endometrium, withdrawal bleed), pregnancy (sustained uterine growth, mammary gland devo), menopause (preceded by anovulatory cycles, vasomotor flashes), post menopause (maintenance of female sex organs, bone loss)
|
|
|
Estrone (E1)
|
other forms of estrogen (see estrogen fxns)
|
|
|
Estriol (E3)
|
other forms of estrogen (see estrogen fxns)
|
|
|
Progesterone
|
prepares endometrium for implantation (luteal), prevents maternal immune rejection of trophoblast (inhibits production of cytolytic cytokines), smooth muscle relaxant (constipation, GI reflux), uterine quiescence (prevents oxytocin receptors + gap junction formation until onset of labor), inhibits ovulation
|
|
|
GnRH
|
pulsative; causes pulsatile release of LH/FSH from pituitary
|
|
|
hCG
|
maintains corpus luteum; finds to LH/CG rectpro to activate adenylyl cyclase and leads to steroidogenesis, binds to TSH receptors
|
|
|
Anti-Mullerian Hormone
|
causes paramesonephric ducts to degenerate, causes a continuous duct system, makes Leydig cells make testosterone
|
|
|
Prostaglandins
|
mediator of labor; E/F, receptors in decidua/myometrium
|
|
|
Oxytocin
|
mediator of labor; potent uterine stimulant, receptors in myometrium, fetal membranes (amnion), decidua
|
|
|
Other labor mediators
|
progesterone (decrease allows increased levels of PGF2 alpha; reduced uterine levels may preceed labor), estrogen (myometrial hypertrophy, upregulates gap junctions + oxytocin receptors), cortisol (from fetus, may trigger labor)
|
