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15 Cards in this Set
- Front
- Back
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FSH
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anterior pituitary
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LH
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anterior pituitary
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Estradiol (E2)
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granulosa cells; pregnenolone --> androstenedione --> aromatase --> estrone --> estradiol via 17B-HSD OR --> 17B-HSD--> testosterone --> aromatase --> estradiol (testosterone converted to estradiol in adipose tissue and liver)
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Estrone (E1)
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in liver from estradiol; in peripheral tissues from androstenedione
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Estriol (E3)
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in liver from estradiol; in peripheral tissues from androstenedione
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Progesterone
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corpus luteum until 10 wks, placenta after 7- 10 wks; cholesterol --> prenenolone (via scc) --> progesterone (via 3B-HSD/KSI)
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GnRH
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hypothalamus (to anterior pituitary by portal circulation)
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Testosterone
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Leydig cells; cholesterol --> pregnenolone via scc --> progesterone via 3B-HSD --> androstenedione --> testosterone via type 3 17B-HSD
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Inhibin B
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Sertoli Cells
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DHT
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Leydig cells; T --> DHT by alpha-reductase <--> 3-a adnrostanediol (via 3a-HSD), more potent than T
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adrenostendione
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theca cells
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hCG
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placenta
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Anti-Mullerian Hormone
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Sertoli cells
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Prostaglandins
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decidua, myometrium, fetal membranes
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Oxytocin
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OT gene upregulated by estrogen
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