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20 Cards in this Set
- Front
- Back
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number of C's in cholesterol
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27
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number of C's in progestans
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21
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number of C's in androgens
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19
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number of C's in estrogens
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18
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precursor for E1
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androstenedione
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precursor for E2
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androstenedione (via testosterone)
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precursor for E3
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16 hydroxy DHEA (from NZ activity of baby's liver)
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androstenedione comes from...
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mom adrenal
theca via CSCC PLACENTA DOES NOT MAKE ANDROGEN!!! |
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function of progestens
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maintain decidua in preg
(mom, hCG, placenta) mammary growth (but inhibit milk production) |
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mechanisms to obtain dominant follicle
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more FSH R's
exceed amt of BP for IGF 1 & 2 inhibin only secreted by dom follicle |
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function of PAPP A
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cleave IGF from binding protein
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mechanisms for ovulation
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LH surge
-rapid growth via IGF 1 & 2 -start 1st meiotic division (suspended in pro one) -stigma (follicle misshape) -proteases & collagenases |
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characteristics of corpus luteum
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granulosa & theca both have LH R's
scar down to albican |
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how can you ID leuteal phase
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blood levels of progesten
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binding of GnRH activates...
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PKC, phosphorylation, nuclear transcription of FSH, LH
AND Ca/Calmodulin secretion |
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what suppresses hypothalamic pulsing
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androgens, estrogen & testosterone
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what suppresses FSH
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inhibin & FSH
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what inhibits release GnRH
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NPY
-inhibited by leptin -athletes/anorexics don't menstruate |
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presence of leptin causes
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inhibition of NPY
removes inhibition of GnRH (regulates ACoA, increases ACTH & TSH) |
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Adrenarche is...
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early signs of puberty from adrenal gland
-weak androgens: DHEA -6-8 years old -pubic hair & breast dvt |
