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20 Cards in this Set

  • Front
  • Back
number of C's in cholesterol
27
number of C's in progestans
21
number of C's in androgens
19
number of C's in estrogens
18
precursor for E1
androstenedione
precursor for E2
androstenedione (via testosterone)
precursor for E3
16 hydroxy DHEA (from NZ activity of baby's liver)
androstenedione comes from...
mom adrenal
theca via CSCC

PLACENTA DOES NOT MAKE ANDROGEN!!!
function of progestens
maintain decidua in preg
(mom, hCG, placenta)
mammary growth
(but inhibit milk production)
mechanisms to obtain dominant follicle
more FSH R's
exceed amt of BP for IGF 1 & 2

inhibin only secreted by dom follicle
function of PAPP A
cleave IGF from binding protein
mechanisms for ovulation
LH surge
-rapid growth via IGF 1 & 2
-start 1st meiotic division (suspended in pro one)
-stigma (follicle misshape)
-proteases & collagenases
characteristics of corpus luteum
granulosa & theca both have LH R's

scar down to albican
how can you ID leuteal phase
blood levels of progesten
binding of GnRH activates...
PKC, phosphorylation, nuclear transcription of FSH, LH

AND

Ca/Calmodulin secretion
what suppresses hypothalamic pulsing
androgens, estrogen & testosterone
what suppresses FSH
inhibin & FSH
what inhibits release GnRH
NPY
-inhibited by leptin
-athletes/anorexics don't menstruate
presence of leptin causes
inhibition of NPY
removes inhibition of GnRH

(regulates ACoA, increases ACTH & TSH)
Adrenarche is...
early signs of puberty from adrenal gland
-weak androgens: DHEA
-6-8 years old
-pubic hair & breast dvt