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15 Cards in this Set

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What type of genome does the influenza virus have? Nucelocapsid?
- segemented RNA with a hical nucleocapsid in a membrane envelope containing 2 glycoproteins
How many subtypes of hemagglutinin are there in the influenza virus? Neuraminidase?
Hemagglutinin: binds to host cells, and four subtypes (H1, H2, H3, H5)
Neuraminidase: cleaves budding viruses; two subtypes (N1, N2)
Define ANTIGENETIC SHIFT
Antigenic shift: major changes due to reassortment of genomes among different strains, including animals.
Define ANTIGENETIC DRIFT
Antigenic drift: subtle changes in the H and N antigens resulting from mutation
Describe 3 types of complications resulting from influenza infection.
Bacterial pneumonia (2ndary infections)
Myosistis: muscle inflammation
Reye's Syndrome: encephalitis, increased risk c/ Aspirin
What type of vaccine is used to immunize against influenza?
Formalin inactivated virus from embryonated eggs
Which virus causes nearly 50% of common colds?
Rhinoviruses
-+ strand RNA with Icoshaedral capsid
How is the common cold virus transmitted?
Respiratory droplets
Enters nose, mouth or eyes c/ 500-1000 infectious virions/mL
What are some other viruses that can cause colds?
Coxsackieviruses
Echoviruses
Adenoviruses
Myxoviruses
Coronaviruses
What does SARS stand for?
Severe Acute Respiratory Syndrome
What type of virus causes SARS?
Coronavirus
+ strand RNA c/ irregular shaped capsid in membrane enveloped with glycoprotiens
What type of virus causes bronchitis? Bronchiolitis?
Bronchitis: parainfluenza virus
RNA virus, helical capsid, envelop
Bronchiolitis: Paramyxovirus/Respiratory syncytial virus
What is the reservoir for hantavirus?
deer mice and other rodents
(arbovirus)
How is the hantavirus transmitted?
Contact c/ aerosolized rodent urine
What is the disease of the hantavirus?
lung failure; capillaries leaked-filling air space