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14 Cards in this Set

  • Front
  • Back

What is the core hormone in the RAA system?

angiotensinogen

Where does angiotensinogen originate?

the liver

What is the first enzyme to act on angiotensinogen?

Renin

What metabolite does angiotensinogen produce?

Angiotensin I

What is the next enzyme to activate angiotensin?

ACE (angiotensin converting enzyme)

What is the metabolite of ACE and Angiotensin I ?

Angiotensin II

What five effects do angiotensin II have?

  1. Increased sympathetic activity
  2. tubular Na+/Cl- reabsorption, K+ secretion, H2O reabsorption
  3. aldosterone secretion
  4. arteriolar vasoconstriction
  5. ADH secretion (antidiuretic hormone, ie. water retention)

What does ADH secretion produce?

retention of Na+/Cl- and H2O, which in turn increases glomerular perfusion

What does arteriolar constriction do?

Increases blood pressure

Where does ACE originate from?

lungs

Where does Aldosterone originate from?

Adrenal cortex (kidney)

Where does renin originate from?

kidney

What stimulates renin production?

a decrease in renal perfusion pressure

What is ADH also known as?

Vasopressin