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20 Cards in this Set

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  • Back
What is the precursor for Angiotension II?
Angiotension I
Which Angiotensin has the most biological activity?
Angiotensin II
What are the actions of Angiotension II?
Vasoconstriction
Release of Aldosterone
Hypertrophy of Heart
What forms Angiotensin I?
Renin
Renin is released in response to ___.
decline in BP
What converts Angiotension I to II?
Angiotensin-Converting Enzyme (ACE)
ACE inhibitors increase levels of ____ and decrease levels of ___.
Bradykinin
Angiotensin II
All ACE inhibitors are administered ___ except for ___.
Orally
Enalaprilat
All ACE inhibitors are pro-drugs except for ____.
Lisinopril
What are ACE inhibitors used for?
Hypertension
MI
Heart Failure
What are the adverse effects of ACE inhibitors?
First-dose hypertension
Cough
Angioedema
Hyperkalemia
Renal Failure
Fetal Injury
What are the contraindications of ACE inhibitors?
Diuretics
Potassium raising drugs
Lithium
NSAIDs
How do ARBs work?
Angiotensin II Receptor Blockers
What is the main difference between ACE inhibitors and ARBs?
Does not cause cough or hyperkalemia
When the drug ends with -pril it is a ___.
ACE inhibitor
When a drug ends with -sartan it is a ___.
ARB
What is the prototype of aldosterone antagonists?
Eplerenone
Eplerenone is a ___.
Aldosterone Antagonist
What is the adverse effect of Eplerenone?
Hyperkalemia
What drug is similar to Eplerenone?
Spironlactone