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20 Cards in this Set
- Front
- Back
What is the precursor for Angiotension II?
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Angiotension I
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Which Angiotensin has the most biological activity?
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Angiotensin II
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What are the actions of Angiotension II?
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Vasoconstriction
Release of Aldosterone Hypertrophy of Heart |
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What forms Angiotensin I?
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Renin
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Renin is released in response to ___.
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decline in BP
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What converts Angiotension I to II?
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Angiotensin-Converting Enzyme (ACE)
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ACE inhibitors increase levels of ____ and decrease levels of ___.
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Bradykinin
Angiotensin II |
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All ACE inhibitors are administered ___ except for ___.
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Orally
Enalaprilat |
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All ACE inhibitors are pro-drugs except for ____.
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Lisinopril
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What are ACE inhibitors used for?
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Hypertension
MI Heart Failure |
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What are the adverse effects of ACE inhibitors?
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First-dose hypertension
Cough Angioedema Hyperkalemia Renal Failure Fetal Injury |
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What are the contraindications of ACE inhibitors?
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Diuretics
Potassium raising drugs Lithium NSAIDs |
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How do ARBs work?
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Angiotensin II Receptor Blockers
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What is the main difference between ACE inhibitors and ARBs?
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Does not cause cough or hyperkalemia
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When the drug ends with -pril it is a ___.
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ACE inhibitor
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When a drug ends with -sartan it is a ___.
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ARB
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What is the prototype of aldosterone antagonists?
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Eplerenone
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Eplerenone is a ___.
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Aldosterone Antagonist
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What is the adverse effect of Eplerenone?
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Hyperkalemia
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What drug is similar to Eplerenone?
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Spironlactone
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