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98 Cards in this Set
- Front
- Back
the area of the kidneys that contains the glomeruli of the nephrons
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cortex
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functional unit of the kidneys
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nephron
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parts of the nephron
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loop of henle, renal corpuscle, proximal convoluted tubule
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Glomerulus and Bowman's capsule together are referred to as the...
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renal corpuscle
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Renin, which is secreted by the JGA, causes the activation of..
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angiotensin 1
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Blood vessels of the kidney are innervated by the...
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sympathetic nervous system
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the end product of protein metabolism excreted in urine
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urea
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determines the final concentration of urine and is secreted by the posterior pituitary
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ADH
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synthesized and secreted by the kidneys, responsible for RBCs, if you have damage to the kidney, that person will have anemia
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Erythropoietin
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Most common type of renal stone is caused by...
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calcium
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How many kidneys does an individual have?
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2
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How many ureters does an individual have?
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2
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tubes that carry the urine down from the functional kidney to the bladder where it is held
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ureters
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A person has 1 bladder. What is the normal volume of bladder content?
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250-300 cc of urine
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Around how many cc does a person feel the need to urinate? And what is this called?
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400 cc, Micturition
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connects the outside of the body to the bladder
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urethra
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Do males or females have a longer urethra? And what problems can this lead to?
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Males have longer urethra, 18-20 cm. Female 3-4 cm. Leads to UTI in women.
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where does the kidney sit in the body?
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retroperitoneal space
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what are some of the functions of the kidney?
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balances water and solute concentration, helps get rid of waste, conserve nutrients, reuglator of acid-base (responsible for base), secretes renin for BP, secretes erythropoietin, activates Vit D
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filtration of the plasma per unit of time, directly related to the perfusion pressure of the glomerular capillaries
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Glomerular Filtration Rate (GFR)
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functional unit of the kidney, regulates filtrate to maintain the body fluid volume, continuously filtering
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nephron
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Kidney receives what % of blood every time the heart pumps?
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20-25%
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movement of substances from the plama to the lumen for getting rid of as a waste product
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tubular secretion
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movement of fluids and solutes from the lumen to the plama, hold on to a nutrient
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tubular reabsorption
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A kidney loses its ability to regulate BP if it drops below...
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70 systolically
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water is reabsorbed without the need for ADH
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Proximal tubule
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water is reabsorbed WITH the need for ADH
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Distal tubule
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primary concentration of urine takes place here
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Loop of Henle
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what are diuretics?
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drugs that make you urinate
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What is the normal creatinine level?
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0.7-1.2
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What is the normal GFR level?
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we want greater than 60 but 125 is normal
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What is the best overall indicator of renal function?
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GFR, then creatinine if no GFR
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Why is creatinine a good blood test for the kidney?
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it is constant (doesn't change whether you are hydrated or not)
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What is the normal BUN (Blood Urea Nitrogen) level?
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10-20, this is the concentration of urea in the blood
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cheapest test to see if there is some type of abnormality
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Urinalysis
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What are some indications of urine abnormality?
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color-cloudy, dark, glucose and ketone level, specific gravity, clarity, pH, sediments, casts, pus
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What is the normal pH of urine?
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5-6.5
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the amount of creatinine cleared from the blood in one minute
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Creatinine Clearance Test (24 hour urine)
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What is the normal Creatinine clearance level?
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90-130
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Age related changes in the renal system include...
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decreased RBF & GFR, amount of nephrons decrease, tubular transport is affected, drug elmination is delayed, response to acid-base loads are prolonged
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What are the 4 major disorders of the kidney?
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Obstuction, UTI, Glomerular Disorders, and Renal Failure
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some sort of decrease in flow, can be at any site along the uniary tract
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Obstruction
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what are the causes of obstruction?
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kidney stones, tumor, pregnancy, prostate enlargement, trauma
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masses of crystals and proteins that are common cause of urinary tract obstruction
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kidney stone
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what are the 3 causes of kidney stones? and what is most common?
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Calcium (most common), uric acid, and struvite
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What are some causes of kidney stones?
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genetics, Southern states (higher temp=more dehydration)
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What is the primary nursing intervention of kidney stones?
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pain management
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clinical manifestations of kidney stones
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nausea, vomiting, pain starts in back and radiates around to groin, hematuria
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Evaluation of kidney stones includes...
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look at unrine pH (will be higher), increase BUN and creatinine, WBC in urine, abdominal scan, CT scan
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Inravenous Pyelogram
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insert dye and watch to see where dye stops. that is where the obstuction is located. MAKE SURE PATIENT ISN'T ALLERGIC TO DYE
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Lithotripsy
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high pitched waves to bust stone up, then has to pass a lot of small stones
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functional UTO that is caused by an interruption of the nerve supply to the bladder
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Neurogenic bladder
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what is Neurogenic bladder often associated with?
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spinal cord injury
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treatment of neurogenic bladder
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antibiotics for infection
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benign tumors that are solid and small, usually surgically removed b/c of ability to metastasize
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renal adenomas
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most common type of renal adenomas
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renal cell carcinoma
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removal of the kidney that is affected
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radical nephrectomy
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how is patient with renal cell carcinoma treated?
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chemo and radiation, removal of affected kidney (Radical Nephrectomy)
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high link to cig smoking, often seen in males 20-40 years old
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bladder tumors
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s/s and diagnosis of bladder tumor
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usually silent disease, hematuria; diagnosis- cystoscopic exam- look for tumor
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treatment of bladder tumor
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remove tumor, chemo and radiation, come back every 3-5 years
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an infection of the bladder
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cystitis
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most common cause of bacterical UTI
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e-coli and staph
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CM of Cystitis
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bacteria causes infection of bladder wall, tissue inflammed, feel urge to urinate, edema causes the urge
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Non-bacterial cystitis
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all the s/s of cystitis, but urine cultures are negative, put on antibiotic
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an infection in the kidney itself (renal pelvis)
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pyelonephritis
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s/s of pyelonephritis
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much sicker individual, systemic, fever, high WBC count, chills, n/v, pus in urine
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you see casts in the urine with what type of UTI
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Pyelonephritis
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persistent or recurring infection of the kidney with inflammation and scarring of the kidney
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chronic pyelonephritis (UTI)
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s/s of Glomerular disorders
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hypertension, edema, elevated BUN, inflammation of glomerulus
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Nephritic sediment
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more hematuria, mild proteinuria
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Nephrotic sediment
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massive proteinura, no hematuria
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post streptococcal, commonly in children 7-10 days after throat infection
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Acute Glomerulonephritis
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effects the basement membranes of the lungs and kidneys, patient will have significant respiratory and kidney probs
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Good-pasture syndrome
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s/s of good-pasture
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bleeding in kidneys and lungs, massive hematuria
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progressive form that develops over a period of time, more commonly than not develops end stage renal disease
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Chronic Glomerulonephritis
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excretion of 3.5 g of protein or more in urine, secondary to a disease such as lupus
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Nephrotic syndrome
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s/s nephrotic syndrome
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edema formation, low albumin levels which helps keep fluid in the vasculature, hyperlipidemia
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diagnosis/Tx of nephrotic syndrome
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based on protein levels, low albumin levels, hyperlipidemia; manage underlying disease, put on low fat diet, restrict salt, diuresis
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decline in renal function to about 25% of normal, GFR 25-30 cc/min
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renal insufficiency
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significant loss of renal function
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renal failure
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when less that 10% of normal kidney function remains
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End Stage Renal Failure
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signs and symptoms of renal failure-or consequences
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uremia
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increased urea levels in the blood
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azotemia
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failure of the kidneys w/out failure to stop making urine; increased creatinine & BUN
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Nonoliguric failure
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abrupt reduction in renal fuction, BP bottomed out for many different reasons, usually reversible
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Acute Renal Failure
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problem above the kidney (BP decrease, shock)
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Pre-renal failure
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problem lies in the kidney such as nephron damage
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Intra-renal
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problem is below the kidneys, on the way outside of the body. usually an obstuction
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Post-renal
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what is the normal cc output of urine per hour?
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30 cc/hr
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progressive, irreversible loss of renal function that affects all body systems
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chronic renal failure
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urinary meatis (male child) is on ventral side of the penis
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Hypospadias
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kidney does not grow in utero, seen on ultrasound
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Renal aplasia
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born without a kidney
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renal agenesis
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most common cancer of children in the UT, highly treatable, horseshoe appearance
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Wilms Tumor
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Bed wetting
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enuresis
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primary enuresis
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never developed the ability to NOT urinate at night
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secondary enuresis
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have learned not to urinate at night, but start back maybe a year later
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