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3 Cards in this Set
- Front
- Back
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Two nephron-related variables influence sodium and water excretion:
Excretion = |
= glomerular filtration
minus tubular reabsorption Tubular reabsorption and GFR are regulated precisely, so that excretion by the kidneys can be exactly matched to intake of water and electrolytes |
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Increased GFR
o Glomerulotubular balance: |
...increased tubular reabsorption of much of the extra sodium chloride filtered
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Increased GFR
o Macula densa feedback: |
...increased NaCl delivery to distal tubule causes afferent arteriolar constriction and return GFR toward normal (so tubules don’t have to work so hard)
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