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40 Cards in this Set
- Front
- Back
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What kind of diuretic is sulfonamide?
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CA inhibitor
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Where in the nephron do CA inhibitors work?
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Proximal tubule
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Which diuretic is helpful in patients with edema accompanied by metabolic alkalosis?
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CA inhibitors
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Which diuretic is used to treat glaucoma, acute mountain sickness?
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CA inhibitors
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Ethacrynic acid is what type of diuretic?
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Loop diuretic
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Which loop diuretic can be administered to a patient with sulfur allergy?
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Ethracrynic acid
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What type of diuretic is furosemide?
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Loop diuretic
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Loop diuretics cause loss of what electrolytes?
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Potassium, magnesium. Calcium not as significant due to PTH and Vit. D feedback
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Which diuretic can be used in treatment of diabetes insipidus?
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Thiazide diuretic
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Chlorthalidone is what type of diuretic?
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Thiazide diuretic
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Which diuretic would be useful in treating hypocalcemia?
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Thiazide diuretic
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What type of diuretic is spironolactone?
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Potassium sparing
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What type of diuretic is amiloride?
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Potassium sparing
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Which transporter do thiazide diuretics inhibit?
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NCC
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Which transporter does amiloride inhibit?
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ENac
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Diuretic treatment for hyperaldosteronism?
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Spironolactone
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Treatment for Liddle Syndrome?
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Amiloride
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How are diuretics delivered to kidney?
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Through anion transporters in proximal tubule
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Treatment of nephrogenic DI?
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Thiazide diuretic
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Drug that can cause diabetes insipidus?
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Lithium
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Drug used to treat SIADH?
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Vaptans
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What makes chlorthalidone a good choice of thiazide diuretic?
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Long half life--especially good for compliance
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Which class of diuretics provides superior CV protection?
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Thiazide diuretics
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What are examples of direct vasodilators in HTN therapy?
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Hydralazine, minoxidil
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Side effect of hydralazine?
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Lupus like effects esp. with slow acetylators
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Minoxidil side effects?
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Hypertrichosis, pericardial effusion
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What receptors do clonidine and methyldopa work on?
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Alpha 2
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Which beta receptor causes release of renin?
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Beta 1
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What receptors do prazosin work on/
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Alpha 1 blocker
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What type of calcium channels do CCBs work on?
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L-type
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What are the three groups of CCBs?
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Dihydropyridine, phenylalkylamine, benzothiazepines
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Dihydropyridines act on calcium channels located where?
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Vascular smooth muscle
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Non-dihydropyridines act on calcium channels located where?
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Heart
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Use of which diuretic causes cough as a side effect?
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ACEI
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Aliskiren is what type of drug?
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Renin inhibitor
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Which antihypertensive drug has been linked to liver problems?
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Aliskiren
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Which diuretic can delay the progression of diabetic renal disease?
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ARBs
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Which anti hypertensive drugs can prolong survival in systolic heart failure and MIs?
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ACEI and ARBs
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Drug therapy for primary hyperaldosteronism?
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Spironolactone
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Drug therapy for pheochromocytoma?
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Phenoxybenzamine (first), propanolol
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