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9 Cards in this Set

  • Front
  • Back

fatty casts (oval fat bodies)


Waxy casts

nephrotic syndrome


advanced renal disease/chronic renal failure

Why do you get a hypercoagulable state with nephrotic syndrome?

Anti-thrombin III loss in urine

Focal Segmental Glomerulos sclerosis


LM


IF


EM

LM: segmental sclerosis and hyalinosis


IF: negative


EM: effacement of foot processes

FSGS


most common in?


-assc with?

most common nephrotic in blacks and hispanics


-HIV, sickle cell, heroin abuse, massive obesity


-IFN treatment, chronic kidney disease

Minimal change disease


LM


IF


EM


-can be assc with?

LM is normal, can see lipid in PCT cells


IF negative


EM effacement


-Hodgkin lymphoma

Membranous nephropathy


LM


IF


EM


-where are the deposits?


-nephrotic presentation of what

LM: diffuse capillary and GBM thickening


IF: granular as a result of immune complex deposition


EM: spike and dome appearance with subepithelial deposits


-nephrotic presentation of SLE

membranous


most common in?


assc with what infections


what drugs


what other things


-HBV, HCV


-NSAIDS, pencillamine


-solid tumors, SLE

Membranoproliferative


Type I


Type II


what is deposited? where?

Type I is subendothelial immune complex (IC) deposits with granular IF, tram track appearance due to GBM splitting caused by mesangial infrowth


Type II is intramembranous IC deposits (dense deposits)

Membranoproliferative


what is type I assc with?

I: HBV, HCV


II: C3 nephritic factor (stabilizes C3 convertase so decreased serum C3 levels)