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9 Cards in this Set
- Front
- Back
fatty casts (oval fat bodies) Waxy casts |
nephrotic syndrome advanced renal disease/chronic renal failure |
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Why do you get a hypercoagulable state with nephrotic syndrome? |
Anti-thrombin III loss in urine |
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Focal Segmental Glomerulos sclerosis LM IF EM |
LM: segmental sclerosis and hyalinosis IF: negative EM: effacement of foot processes |
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FSGS most common in? -assc with? |
most common nephrotic in blacks and hispanics -HIV, sickle cell, heroin abuse, massive obesity -IFN treatment, chronic kidney disease |
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Minimal change disease LM IF EM -can be assc with? |
LM is normal, can see lipid in PCT cells IF negative EM effacement -Hodgkin lymphoma |
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Membranous nephropathy LM IF EM -where are the deposits? -nephrotic presentation of what |
LM: diffuse capillary and GBM thickening IF: granular as a result of immune complex deposition EM: spike and dome appearance with subepithelial deposits -nephrotic presentation of SLE |
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membranous most common in? assc with what infections what drugs what other things
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-HBV, HCV -NSAIDS, pencillamine -solid tumors, SLE |
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Membranoproliferative Type I Type II what is deposited? where? |
Type I is subendothelial immune complex (IC) deposits with granular IF, tram track appearance due to GBM splitting caused by mesangial infrowth Type II is intramembranous IC deposits (dense deposits) |
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Membranoproliferative what is type I assc with? |
I: HBV, HCV II: C3 nephritic factor (stabilizes C3 convertase so decreased serum C3 levels) |