Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key


Play button


Play button




Click to flip

8 Cards in this Set

  • Front
  • Back
Difference between Wegner's Granulomatosis, Microscopic PAN
Wegner's: P-ANCA, PAN: C-ANCA
Wegner's: Presents with otitis media, sinusitis, keratoconjunctivitis, pneumonia
Activity Indicators of SLE
Globerular Cell Proliferation
Leukocyte Exudation
Cellular Crescents
Fibrinoid Necrosis
Hyaline Deposits
Hyalin thrombi
Interstitial Mononuclear Inflammatory Infiltrate
Wire Loops
Criteria for Diagnosis of SLE
Malar Rash
Discoid Rash
Oral Ulcers
Renal Disorders
Neurologic Disorders
Hematologic Disorders
Immunologic Disorders
Glomerular Changes in DM
Basement Membrane Thickening
Diffuse Glomerulosclerosis- increased Mesangial Matrix
Nodular Glomerulosclerosis (Kilmmelstiel-Wilson): increased mes. matrix with nodular appearance
Diffuse linear IgG staining along capillary loops, tubular BM and Bowman's Capsule
Difference between Microscopic and Macroscopic Polyarteritis Nodosa
Classic (Macroscopic)- more commoen in men, during 5th-6th decade, medium arteries like coronaries, spares lung, lesion of different ages in same organ

Hypersensitivity Angitis (Microscopic Polyarteritis): Hx of allergy common. All lesions of same age. Involves Lung
Amyloidosis Classification Themes
Primary- Immunocyte Dyscrasias
Secondary- chronic inflammation: rheumatoid arthritis, ankylosing spondylitis, IBS, TB, chronic osteomyelitis
Hereditary- AA fibril, Familial Mediterranean Fever
AL- immunocyte dyscrasias: heart, tongue, GI, nerves, skin
AA- Serum Amyloid A (SAA)- a HDL, synthesized in liver, found in chronic inflammatory conditions- involves liver, kidney, adrenal, spleen
Renal Manifestations of DM
Glomerular Changes
Fibrous Crescents
Interstitial Fibrosis
Alport Syndrome: Histo, IF, ultrastructural features
Defect of Type IV Collagen, alpha 5 chain

Histo- Glomerular Proliferation/Sclerosis, Increased Mesangial Matrix, fetal glomeruli, Foam Cells, Tubular Atrophy, Interstitial Fibrosis
IF- Negative
EM- Attenuation, thickening, splitting, lamellation of BM