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6 Cards in this Set
- Front
- Back
what is the most common, and most significant, cause of acute renal failure?
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ATN, acute tubular decrosis
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describe the clinical picture seen in ATN, acute tubular necrosis. describe the successive stages that can develop
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TUBULAR CELL CASTS and RBCs in urine, oliguria, hyperKalemia
stage 2 - becomes polyuria, low Na, K and Ca -stage 3 - after 2 weeks, regeneration has occured - complications will occur |
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how do areas of necrosis differ in toxic vs ischemic ATN
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toxic - diffuse necrosis (prox tubule), intact BM
ischemic - segmental/dispersed, with rupture of BM - tubulorhexis |
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etiology of toxic ATN and ischemic ATN?
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toxic - ethylene glycol (will have Ca Oxalate crystals), antibacterials (aminoglycosides, etc),
ischemic - hypovolemic shock (septicemia, burns, mismatch tranfusion), cardiogenic shock |
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etiology and Dx factors of acute vs chronic interstitial nephritis:
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acute: caused by methicillin, Dx with high eosinophils in urine and IgE
chronic: caused by aspirin and phenacetin, lead to papillary necrosis, will see lymphocytes in urine |
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renal changes after multiple myeloma
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obstruction in tubules due to viscous light chain casts
-amyloidosis, calcinosis secondary to bone destruction |