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44 Cards in this Set

  • Front
  • Back

The type of nephron responsible for renal concentration is the:

Juxtaglomerular

The function of the peritubular capillaries is:

Reabsorption & Secretion

Blood flows through the nephron/kidneys in the following order:

1. Afferent arteriole


2. Peritubular capillaries


3. Vasa recta


4. Efferent arteriole

Filtration of protein is prevented in the glomerulus by:

The glomerular filtration barrier

The renin - angiotensin - aldosterone system is responsible:

1. Vasoconstriction of the efferent arteriole


2. Reabsorbing sodium


3. Releasing aldosterone

The primary chemical affected by the renin - angiotensin - aldosterone system is:

Sodium

Secretion of renin is stimulated by:

Macula densa cells

The hormone aldosterone is responsible for:

Sodium retention

The fluid leaving the glomerulus has a specific gravity of:

1.010

For active transport to occur, a chemical:

Must combine with a carrier protein to create electrochemical energy

Which of the tubules is impermeable to water?

Ascending loop of Henle

Glucose will appear in the urine when the:

1. Blood level of glucose is 200 mg/dL


2. Tm for glucose is reached


3. Renal threshold for glucose is exceeded

Concentration of the tubular filtrate by the countercurrent mechanism depends on:

1. High salt concentration in the medulla



2. Water - impermeable walls of the ascending loop of Henle



3. Reabsorption of sodium and chloride from the Ascending loop of Henle

ADH regulates the final urine concentrations by controlling:

Tubular permability

Decreased production of ADH:

Produces a high urine volume

Bicarbonate ions filtered by the glomerulus are returned to the blood:

Combined with hydrogen ions

If ammonia is not produced by the distal convoluted tubule, the urine pH will be:

Basic

The largest source of error in creatinine clearance tests is:

Improperly timed urine specimens

Clearance tests used to determine the glomerular filtration rate must measure substances that are

Neither reabsorbed or secreted by the tubules

Performing a clearance test using radionucleotides:

1. Eliminates the need to collect urine



2. Provides visualization of the filtration

Variable that are included in the MDRD - IDSM estimated creatinine clearance calculations include all of the following:

Serum Creatinine



Age



Gender

An advantage to using cystatin C to monitor GFR is that:

It is not secreted by the tubules

Solute dissolved in solvent will:

Lower the freezing point

Substances that may interfere with freezing point measurement of urine and serum osmolarity include:

Ethanol



Lactic Acid



Lipids

Clinical osmometers use NaCl as a reference solution because

NaCl is partially ionized similar to the composition of urine

The normal serum osmolarity is

275 to 300 mOsm

After controlled fluid intake, the urine to serum osmolarity ratio should be atleast

1:1

To provide an accurate measure of renal blood flow, a test substance should be completely:

Cleared on each contact with functional renal tissue

Renal tubular acidosis can be caused by the

inability to produce an acidic urine due to impaired production of ammonia

Test performed to detect renal tubular acidosis after administering an ammonium chloride load include all of the following except:

Arterial pH

Function of the Kidney

Produces Urine

Function of the Ureter

Transports urine to the urinary bladder

Function of the Urinary bladder

Temporarily stores urine prior to elimination

Function of the Urethra

Conducts urine to exterior; in males transports semen as well

How is blood supplied to the kidneys?

Via the renal arteries which are branches of the abdominal aorta

How is blood drained from the kidneys?

Via renal veins which are branches of the inferior vena cava

What is the renal functions?

1. Renal blood flow



2. Glomerular filtration



3. Tubular reabsorption



4. Tubular Secretion

Where is the Glomerulus located?

Bowman's Capsule

What is the factors of filtration?

1. Cellular Structure



2. Hydrostatic and oncotic pressure



3. Renin - angiotensin - aldosterone system

What are the three cellular layer of kidney?

1. Capillary wall



2. Basement membrane



3. Bowman's capsule inner layer

How much percent of Albumin is in our urine?

60%

Water reabsorption occurs throughout the nephron except?

Ascending loop of Henle

What does renal function tests evaluate?

1. Glomerular filtration



2. Tubular reabsorption



3. Tubular Secretion



4. Renal blood flow

Why would creatine values decrease?

Dehydration



COPH & CHF - impairment of blood supply



Glomertitis



Nephrotoxic