Renal Equations

Front 1

Renal Clearance

Back 1

C = UV/ P

C= clearance of x

U= urine concentration of x

P= plasma concentration of x

V= urine flow rate

Front 2

Renal clearance compared to GFR

Back 2

• C < GFR : Net tubular resorption of x
• C > GFR: Net tubular secretion of x
• C = GFR: no net secretion or resorption

Front 3

Glomerular filtration rate:

Back 3

GFR = (U) (V/P) = C

Can use inulin to calculate

• U = Urine concentration of inulin
• V= Urine flow rate
• P= Plasma concentration of inulin
• C = Clearance of inulin

Creatinine clearance is an approximate measure of GFR

Front 4

What is the equation for effective renal plasma flow?

Back 4

eRPF = (UPAH) ( V/PPAH) = CPAH

Front 5

What is renal blood flow if renal plasma flow is known?

Back 5

RBF = RPF/ (1-Hct)

1-Htc : volume flowing through kidneys that is plasms

Front 6

Filtration fraction

Back 6

FF= GFR/ RPF

Front 7

How do you calculate resorption and secretion?

Back 7

Filtered load = Filtered load * P

Excretion Rate= V * U

Filtered > Excreted → substance is being reabsorbed

Filtered < Excreted → substance is being secreted

Front 8

At what plasma level of glucose does glucosuria begin?

Back 8

200 mg/dL

Front 9

At what glucose plasma level are glucose transporters fully saturated?

Back 9

375 mg/dL