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11 Cards in this Set
- Front
- Back
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Blood pressure control |
-feedback mechanisms work to maintain a MAP -they do this by sympathetic regulation |
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Negative feedback mechanism |
Baroreceptors detect change---> sent to NTS--->Effector systems |
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High pressure baroreceptors |
-Carotid sinus (CNIX) -Aortic Arch (CNX) -Renal afferent arteriole |
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Low pressure baroreceptors |
-Vena Cava -Right atrium -Pulmonary artery |
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Function of baroreceptors |
High pressure : Increase CO---> Increase stretch---> Increase afferent to NTS ---> Regulation
Low pressure: Increase VR ---> Increase stretch---> Increase affront to NTS ---> Regulation |
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Carotid sinus nerve firing |
-Threshold is 50 mmHg -sustained at 200 mmHg |
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Cardiovascular integration center |
Increase BP---> Baroreceptor discharge increases---> Glutamate (neurotransmitter)---> Stimulates GABA---> secrete inhibitory neurons to vasomotor center---> decrease efferent tonic discharge---> Decrease HR, contractility, and vasodilation ---> Decrease BP |
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Carotid massage |
-Manual stimulation of baroreceptors -Increases afferent firing to NTS -Lower HR and BP |
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Chronic hypertension |
-High pressure baroreceptors not effective -Adapt to the increase stretch |
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Renin Angiotensin Aldosterone System |
1. BP falls ---> afferent arterioles release renin (vice versa) 2.Renin acts on angiotensinogen--->angiotensin 1 3.ACE cleaves angiotensin 1 to angiotensin II
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Angiotensin II |
-Constricts resistance vessels (via AT1 receptors) -acts on adrenal cortex to release aldosterone causing kidneys to increase Na+ and fluid retention -stimulates release of ADH which increases fluid retention |
