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20 Cards in this Set

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  • Back
What is the Ideal Body Weight equation for adult males?
IBW (kg) = 50 + (2.3 x height in inches over 5 ft)
What is the Ideal Body Weight equation for adult females?
IBW (kg) = 45.5 + (2.3 x height in inches over 5 ft)
According to course notes, what is the average weight of an adult?
70 kg
Young’s rule is used to estimate the pediatric dose of a drug from the adult dose. What is the equation for Young’s rule?
[Age / (Age + 12)] x Adult dose = Dose for Child
What is an intimate mixture of dry, finely divided drugs and/or chemicals, which, upon the addition of suitable vehicles, yields a solution?
Powder, for Solution
What is an intimate mixture of dry, finely divided drugs and/or chemicals, which, upon the addition of suitable vehicles, yields a suspension (a liquid preparation containing the solid particles dispersed in a liquid vehicle)?
Powder, for Suspension
What is a sterile preparation intended for reconstitution to form a suspension for parenteral use?
Injection, Powder, for Suspension
What is a sterile preparation intended for reconstitution to form a solution for parenteral use?
Injection, Powder for Solution
What is a small medicinal particle or grain made available in its more stable dry form, to be reconstituted with solvent just before dispensing, that is prepared to contain not only medicinal agent, but also the colorants, flavorants, and any other desired pharmaceutical ingredient?
Granule, for Solution
What is a small particle or grain containing a medicinal agent in a dry mixture, usually composed of sodium bicarbonate, citric acid, and tartaric acid, which, when contacted with water, has the capability to release gas, resulting in effervescence?
Granule, Effervescent
What is a small medicinal particle or grain made available in its more stable dry form, to be reconstituted with solvent just before dispensing to form a suspension, prepared to contain not only the medicinal agent, but also the colorants, flavorants, and any other desired pharmaceutic ingredient?
Granule, for Suspension
What is a small medicinal particle or grain made available in its more stable dry form, to be reconstituted with solvent just before dispensing to form a suspension to effect a slow release of the drug over an extended period of time in order to maintain constant drug levels in the blood or target tissue?
Granule, for Suspension, Extended Release
What is a dosage form, intended for solution, that is prepared by freeze drying, i.e. lyophilization, and intended for subsequent addition of liquid to create a solution that conforms in all respects to the requirements for injections?
Injection, Powder, Lyophilized, for Solution
What is dosage form, intended for the preparation of a suitable fluid medium containing suspended solids - prepared by lyophilization - that conforms in all respects to the requirements for sterile suspensions, and is intended for parenteral use?
Injection, Powder, Lyophilized, for Suspension
What is a sterile freeze dried preparation, intended for reconstitution for parenteral use, which has been formulated in a manner that would allow liposomes to be formed upon reconstitution?
Injection, Powder, Lyophilized, for Liposomal Suspension
What is a sterile, freeze dried preparation, intended for reconstitution for parenteral use, which has been formulated in a manner to allow at least a reduction in dosing frequency as compared to that drug presented as a conventional dosage form?
Injection, Powder, Lyophylized, for Suspension, Extended Release
What are dry formulations which require mixing with water prior to administration?
Suspensions for Reconstitution
What are several examples of typical suspending agents, capable of dispersing readily by shaking? [Lecutre notes list four]
Sodium carboxymethylcellulose (NaCMC), microcrystalline cellulose w/ NaCMC, carrageenans, and xantham gum
Preparations for suspensions for reconstitution fall into one of three classes. What are these classes?
1) Powder blends, 2) Granulations, & 3) A combination of powder blends and granulations.
Tests done on reconstituted solutions include?
Dose uniformity, sterility, and stability testing