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23 Cards in this Set

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  • Back
hormones from anterior pituitary
FLAT PiG

FSH
LSH
ACTH
TSH
Prolactin
GH
GH functions
anti-insulin
fat utilization at expense of protein
GH regulation
stim by GHRH
inhib by somatostatin
(also inhibits TSH)
feedback inhibition & IGF inhibition

synergistic w/TH
affected by hypothal tumors
disorders involving GH
hypothal tumor (defic)

gigantism & acromegaly (excess)
TSH subunit w/low specificity
alpha subunit
shared by LH, FSH, HCG
hypothal stim of ACTH
CRH
production of cortisol
CRH from Hypothal
ACTH from ant pit

activate POMC pathway
(also produce endorphins, lipotropin, melanocyte stim hormone)
hypothalamic regulation of prolactin
DA inhibits

hypothal (GRH, TRH) & estrogen (systemic) stimulates
prolactin excess
amenorrhea & galatorrhea in women

ED, impotence in men
hypothalamic regulation of LH & FSH
(gonadotropins)

GnRH stims

testost, estro & progest inhibit
functions of oxytocin
milk letdown
uterine ctx
maternal nurturing behaviors
regulation of oxytocin
stim by nipple stim

inhib by catecholamines
hypothalamic peptides acting on pit
GnRH
CRH
TRH
GHRH
severed stalk of pit will suppress...
all ant pit hormones EXCEPT prolactin

"hypophysiotropic hormones"
hypophysiotropic hormones
TSH, GH
LH, FSH, ACTH
stimulators of ADH
osmoreceptors (hypothal)
baroreceptors (atrial & carotid)
nausea
nicotine, mophine
AT II
hypoxia, hypercapnea
acidophilic cells
somatotroph (GH)
Lactotroph (prolactin)
somatomammotroph (GH, Prolac)
basophilic cells
corticotroph
gonadotroph (LH, FSH)
thyrotroph
mech of stim of cortisol production
CRH stim
ACTH causes
cAMP activation of cortisol, aldosterone, androgens
somatomammotropins
GH
prolactin
placental lactogen
peptide hormone families
somatomammotropins
(GH, Prolactin, Placental Lactogen)
corticotropins
(ACTH, MSH, LPH, endorphin)
glycoproteins
(TSH, LH, FSH, hCG)
tx for pit insuff
essential hormones
-TSH
-ADH
-Cortisol

QOL hormones
-estrogen
-testosterone
tx for pit adenomas
prolactinomas
-Bromocriptine (DA agonist)

GH & TSH
-octreotide (somatostatin analog)

surg, irrad